Pathogenetic treatment for neurotrophic keratopathy

Introduction. Continuous soft contact lens (SCL) wearing can result in development of neurotrophic keratopathy. Treatment of this pathology is long-term and, in general, symptomatic: tear-substitute, epithelizing, vitaminous, antibacterial, anti-inflammatory therapy. Purpose. To improve a correc...

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Main Authors: T. B. Gaidamaka, T. A. Veliksar, G. I. Drozhzhyna, T. M. Serebrina
Format: Article
Language:English
Published: Ukrainian Society of Ophthalmologists 2018-04-01
Series:Journal of Ophthalmology
Subjects:
Online Access:https://www.ozhurnal.com/en/archive/2018/2/2-fulltext
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author T. B. Gaidamaka
T. A. Veliksar
G. I. Drozhzhyna
T. M. Serebrina
author_facet T. B. Gaidamaka
T. A. Veliksar
G. I. Drozhzhyna
T. M. Serebrina
author_sort T. B. Gaidamaka
collection DOAJ
description Introduction. Continuous soft contact lens (SCL) wearing can result in development of neurotrophic keratopathy. Treatment of this pathology is long-term and, in general, symptomatic: tear-substitute, epithelizing, vitaminous, antibacterial, anti-inflammatory therapy. Purpose. To improve a correction method for metabolic alterations in corneal tissues in continuous-SCL-wear-associated neurotrophic keratopathy through using transorbital electrophoresis with 1% thiotriazoline. Material and Methods. We developed a method of treatment for neurotrophic keratopathy which includes a 10 day course of daily transorbital electrophoresis with 1% thiotriazoline as a part of complex therapy. We applied for approval of Author's certificate (application No U 201710621 dated 01 November 2017). Results. Clinical cases of treatment of stage 1 neurotrophic keratopathy are reported. Conclusion. The proposed treatment enables in a short term to significantly decrease pathological changes in corneal tissues in stage 1 neurotrophic keratopathy, to increase comfort in the eyes, to prevent severe complications of neurotrophic keratopathy and soft contact lens wearing.
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spelling doaj.art-7f1173a321e24721b2ab7178921352152023-12-25T10:49:02ZengUkrainian Society of OphthalmologistsJournal of Ophthalmology2412-87402018-04-01271010.31288/oftalmolzh/2018/2/710Pathogenetic treatment for neurotrophic keratopathy T. B. Gaidamaka0T. A. Veliksar1G. I. Drozhzhyna2T. M. Serebrina3Filatov Institute of Eye Diseases and Tissue TherapyFilatov Institute of Eye Diseases and Tissue TherapyFilatov Institute of Eye Diseases and Tissue TherapyFilatov Institute of Eye Diseases and Tissue TherapyIntroduction. Continuous soft contact lens (SCL) wearing can result in development of neurotrophic keratopathy. Treatment of this pathology is long-term and, in general, symptomatic: tear-substitute, epithelizing, vitaminous, antibacterial, anti-inflammatory therapy. Purpose. To improve a correction method for metabolic alterations in corneal tissues in continuous-SCL-wear-associated neurotrophic keratopathy through using transorbital electrophoresis with 1% thiotriazoline. Material and Methods. We developed a method of treatment for neurotrophic keratopathy which includes a 10 day course of daily transorbital electrophoresis with 1% thiotriazoline as a part of complex therapy. We applied for approval of Author's certificate (application No U 201710621 dated 01 November 2017). Results. Clinical cases of treatment of stage 1 neurotrophic keratopathy are reported. Conclusion. The proposed treatment enables in a short term to significantly decrease pathological changes in corneal tissues in stage 1 neurotrophic keratopathy, to increase comfort in the eyes, to prevent severe complications of neurotrophic keratopathy and soft contact lens wearing. https://www.ozhurnal.com/en/archive/2018/2/2-fulltextneurotrophic keratopathycontact lensesthiotriazolineelectrophoresis
spellingShingle T. B. Gaidamaka
T. A. Veliksar
G. I. Drozhzhyna
T. M. Serebrina
Pathogenetic treatment for neurotrophic keratopathy
Journal of Ophthalmology
neurotrophic keratopathy
contact lenses
thiotriazoline
electrophoresis
title Pathogenetic treatment for neurotrophic keratopathy
title_full Pathogenetic treatment for neurotrophic keratopathy
title_fullStr Pathogenetic treatment for neurotrophic keratopathy
title_full_unstemmed Pathogenetic treatment for neurotrophic keratopathy
title_short Pathogenetic treatment for neurotrophic keratopathy
title_sort pathogenetic treatment for neurotrophic keratopathy
topic neurotrophic keratopathy
contact lenses
thiotriazoline
electrophoresis
url https://www.ozhurnal.com/en/archive/2018/2/2-fulltext
work_keys_str_mv AT tbgaidamaka pathogenetictreatmentforneurotrophickeratopathy
AT taveliksar pathogenetictreatmentforneurotrophickeratopathy
AT gidrozhzhyna pathogenetictreatmentforneurotrophickeratopathy
AT tmserebrina pathogenetictreatmentforneurotrophickeratopathy