Recent Advances in Synthetic Routes to Azacycles
A heterocycle is an important structural scaffold of many organic compounds found in pharmaceuticals, materials, agrochemicals, and biological processes. Azacycles are one of the most common motifs of a heterocycle and have a variety of applications, including in pharmaceuticals. Therefore, azacycle...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-03-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1420-3049/28/6/2737 |
| _version_ | 1797609861098242048 |
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| author | Anh Thu Nguyen Hee-Kwon Kim |
| author_facet | Anh Thu Nguyen Hee-Kwon Kim |
| author_sort | Anh Thu Nguyen |
| collection | DOAJ |
| description | A heterocycle is an important structural scaffold of many organic compounds found in pharmaceuticals, materials, agrochemicals, and biological processes. Azacycles are one of the most common motifs of a heterocycle and have a variety of applications, including in pharmaceuticals. Therefore, azacycles have received significant attention from scientists and a variety of methods of synthesizing azacycles have been developed because their efficient synthesis plays a vital role in the production of many useful compounds. In this review, we summarize recent approaches to preparing azacycles via different methods as well as describe plausible reaction mechanisms. |
| first_indexed | 2024-03-11T06:07:26Z |
| format | Article |
| id | doaj.art-7f138221d0ed4519b8bc12388678ae62 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-11T06:07:26Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-7f138221d0ed4519b8bc12388678ae622023-11-17T12:54:29ZengMDPI AGMolecules1420-30492023-03-01286273710.3390/molecules28062737Recent Advances in Synthetic Routes to AzacyclesAnh Thu Nguyen0Hee-Kwon Kim1Department of Nuclear Medicine, Jeonbuk National University Medical School and Hospital, Jeonju 54907, Republic of KoreaDepartment of Nuclear Medicine, Jeonbuk National University Medical School and Hospital, Jeonju 54907, Republic of KoreaA heterocycle is an important structural scaffold of many organic compounds found in pharmaceuticals, materials, agrochemicals, and biological processes. Azacycles are one of the most common motifs of a heterocycle and have a variety of applications, including in pharmaceuticals. Therefore, azacycles have received significant attention from scientists and a variety of methods of synthesizing azacycles have been developed because their efficient synthesis plays a vital role in the production of many useful compounds. In this review, we summarize recent approaches to preparing azacycles via different methods as well as describe plausible reaction mechanisms.https://www.mdpi.com/1420-3049/28/6/2737azacycles<i>N</i>-heterocyclesheterocyclic synthesis |
| spellingShingle | Anh Thu Nguyen Hee-Kwon Kim Recent Advances in Synthetic Routes to Azacycles Molecules azacycles <i>N</i>-heterocycles heterocyclic synthesis |
| title | Recent Advances in Synthetic Routes to Azacycles |
| title_full | Recent Advances in Synthetic Routes to Azacycles |
| title_fullStr | Recent Advances in Synthetic Routes to Azacycles |
| title_full_unstemmed | Recent Advances in Synthetic Routes to Azacycles |
| title_short | Recent Advances in Synthetic Routes to Azacycles |
| title_sort | recent advances in synthetic routes to azacycles |
| topic | azacycles <i>N</i>-heterocycles heterocyclic synthesis |
| url | https://www.mdpi.com/1420-3049/28/6/2737 |
| work_keys_str_mv | AT anhthunguyen recentadvancesinsyntheticroutestoazacycles AT heekwonkim recentadvancesinsyntheticroutestoazacycles |