The Protective Effect of Dabigatran and Rivaroxaban on DNA Oxidative Changes in a Model of Vascular Endothelial Damage with Oxidized Cholesterol

The Protective Effect of Dabigatran and Rivaroxaban on DNA Oxidative Changes in a Model of Vascular Endothelial Damage with Oxidized Cholesterol

Background: Atherosclerotic plaques are unstable, and their release may result in thrombosis; therefore, currently, antiplatelet therapy with anticoagulants is recommended for the treatment of acute coronary syndrome. The aim of this study was to assess the effect of oxidized cholesterol on human um...

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Bibliographic Details
Main Authors: Ewelina Woźniak, Marlena Broncel, Bożena Bukowska, Paulina Gorzelak-Pabiś
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:International Journal of Molecular Sciences
Subjects:
dabigatran
rivaroxaban
dna oxidative damage
vascular endothelial damage
oxidized cholesterol
reactive oxygen species
dna bases
Online Access:https://www.mdpi.com/1422-0067/21/6/1953

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