Copy number variation of mitochondrial genes in Pneumocystis jirovecii according to the fungal load in BAL specimens

AbstractPneumocystis jirovecii is an unculturable fungus and the causative agent of Pneumocystis pneumonia, a life-threatening opportunistic infection. Although molecular diagnosis is often based on the mtLSU rRNA mitochondrial gene due to its greater sensitivity, physiology and the dynamics of the...

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Main Authors: clara valero, Maria Jose Buitrago, Maud Gits-Muselli, Marion Benazra, Aude Sturny-Leclere, Samia Hamane, Nicolas Guigue, Stephane Bretagne, Alexandre Alanio
Format: Article
Jezik:English
Izdano: Frontiers Media S.A. 2016-09-01
Serija:Frontiers in Microbiology
Teme:
Online dostop:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01413/full