Streptococcal toxic shock syndrome in the intensive care unit

Abstract The streptococcal toxic shock syndrome is a severe complication associated with invasive infections by group A streptococci. In spite of medical progresses in the care of patients with septic shock during the last decades, this condition has remained associated with a high mortality. Early...

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Main Authors: Marylin Schmitz, Xavier Roux, Benedikt Huttner, Jérôme Pugin
Format: Article
Language:English
Published: SpringerOpen 2018-09-01
Series:Annals of Intensive Care
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13613-018-0438-y
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author Marylin Schmitz
Xavier Roux
Benedikt Huttner
Jérôme Pugin
author_facet Marylin Schmitz
Xavier Roux
Benedikt Huttner
Jérôme Pugin
author_sort Marylin Schmitz
collection DOAJ
description Abstract The streptococcal toxic shock syndrome is a severe complication associated with invasive infections by group A streptococci. In spite of medical progresses in the care of patients with septic shock during the last decades, this condition has remained associated with a high mortality. Early recognition and multidisciplinary management are key to the care of patients with streptococcal toxic shock syndrome, with intensive and appropriate intensive support of failing organs, rapid diagnosis of infectious source(s), and surgical management. The epidemiology and risk factors for streptococcal toxic shock syndrome remain to be better studied, including the possible causal role of exposure to nonsteroidal anti-inflammatory drugs. In this review article, the authors review the current knowledge of streptococcal toxic shock syndrome and discuss the pathophysiology as well as its supportive and specific treatment.
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spelling doaj.art-7f1b34a6f1d84289917415f299ec41a42022-12-22T03:42:27ZengSpringerOpenAnnals of Intensive Care2110-58202018-09-018111010.1186/s13613-018-0438-yStreptococcal toxic shock syndrome in the intensive care unitMarylin Schmitz0Xavier Roux1Benedikt Huttner2Jérôme Pugin3Division of Intensive Care, Faculty of Medicine Geneva, University Hospitals of Geneva, University of GenevaDivision of Intensive Care, Faculty of Medicine Geneva, University Hospitals of Geneva, University of GenevaDivision of Infectious Diseases, Faculty of Medicine Geneva, University Hospitals of Geneva, University of GenevaDivision of Intensive Care, Faculty of Medicine Geneva, University Hospitals of Geneva, University of GenevaAbstract The streptococcal toxic shock syndrome is a severe complication associated with invasive infections by group A streptococci. In spite of medical progresses in the care of patients with septic shock during the last decades, this condition has remained associated with a high mortality. Early recognition and multidisciplinary management are key to the care of patients with streptococcal toxic shock syndrome, with intensive and appropriate intensive support of failing organs, rapid diagnosis of infectious source(s), and surgical management. The epidemiology and risk factors for streptococcal toxic shock syndrome remain to be better studied, including the possible causal role of exposure to nonsteroidal anti-inflammatory drugs. In this review article, the authors review the current knowledge of streptococcal toxic shock syndrome and discuss the pathophysiology as well as its supportive and specific treatment.http://link.springer.com/article/10.1186/s13613-018-0438-yStreptococcal toxic shock syndromeNecrotizing fasciitisGroup A streptococcusSepsisBacterial toxins
spellingShingle Marylin Schmitz
Xavier Roux
Benedikt Huttner
Jérôme Pugin
Streptococcal toxic shock syndrome in the intensive care unit
Annals of Intensive Care
Streptococcal toxic shock syndrome
Necrotizing fasciitis
Group A streptococcus
Sepsis
Bacterial toxins
title Streptococcal toxic shock syndrome in the intensive care unit
title_full Streptococcal toxic shock syndrome in the intensive care unit
title_fullStr Streptococcal toxic shock syndrome in the intensive care unit
title_full_unstemmed Streptococcal toxic shock syndrome in the intensive care unit
title_short Streptococcal toxic shock syndrome in the intensive care unit
title_sort streptococcal toxic shock syndrome in the intensive care unit
topic Streptococcal toxic shock syndrome
Necrotizing fasciitis
Group A streptococcus
Sepsis
Bacterial toxins
url http://link.springer.com/article/10.1186/s13613-018-0438-y
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AT xavierroux streptococcaltoxicshocksyndromeintheintensivecareunit
AT benedikthuttner streptococcaltoxicshocksyndromeintheintensivecareunit
AT jeromepugin streptococcaltoxicshocksyndromeintheintensivecareunit