Translational Assessment of Drug‐Induced Proximal Tubule Injury Using a Kidney Microphysiological System
Drug‐induced kidney injury, a major cause of acute kidney injury, results in progressive kidney disease and is linked to increased mortality in hospitalized patients. Primary injury sites of drug‐induced kidney injury are proximal tubules. Clinically, kidney injury molecule‐1, an established tubule‐...
Main Authors: | Christian Maass, Nathan B. Sorensen, Jonathan Himmelfarb, Edward J. Kelly, Cynthia L. Stokes, Murat Cirit |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-05-01
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Series: | CPT: Pharmacometrics & Systems Pharmacology |
Online Access: | https://doi.org/10.1002/psp4.12400 |
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