A Screen for Epigenetically Silenced microRNA Genes in Gastrointestinal Stromal Tumors.
Dysregulation of microRNA (miRNA) has been implicated in gastrointestinal stromal tumors (GISTs) but the mechanism is not fully understood. In this study, we aimed to explore the involvement of epigenetic alteration of miRNA genes in GISTs.GIST-T1 cells were treated with 5-aza-2'-deoxycytidine...
Main Authors: | Mai Isosaka, Takeshi Niinuma, Masanori Nojima, Masahiro Kai, Eiichiro Yamamoto, Reo Maruyama, Takayuki Nobuoka, Toshirou Nishida, Tatsuo Kanda, Takahiro Taguchi, Tadashi Hasegawa, Takashi Tokino, Koichi Hirata, Hiromu Suzuki, Yasuhisa Shinomura |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4516245?pdf=render |
Similar Items
-
Impact of Rechallenge with Imatinib in Patients with Advanced Gastrointestinal Stromal Tumor after Failure of Imatinib and Sunitinib
by: Akira Sawaki, et al.
Published: (2014-01-01) -
TET1 Depletion Induces Aberrant CpG Methylation in Colorectal Cancer Cells.
by: Masahiro Kai, et al.
Published: (2016-01-01) -
Low-Frequency IL23R Coding Variant Associated with Crohn's Disease Susceptibility in Japanese Subjects Identified by Personal Genomics Analysis.
by: Kei Onodera, et al.
Published: (2015-01-01) -
DOT1L inhibition blocks multiple myeloma cell proliferation by suppressing IRF4-MYC signaling
by: Kazuya Ishiguro, et al.
Published: (2019-01-01) -
A novel method, digital genome scanning detects <it>KRAS </it>gene amplification in gastric cancers: involvement of overexpressed wild-type KRAS in downstream signaling and cancer cell growth
by: Yanagihara Kazuyoshi, et al.
Published: (2009-06-01)