Myeloperoxidase, modified lipoproteins, and atherogenesis
Numerous lines of evidence implicate a role for myeloperoxidase (MPO) in the pathogenesis of atherosclerosis. Enriched within vulnerable plaque, MPO serves as an enzymatic source of eicosanoids and bioactive lipids and generates atherogenic forms of both low- and high-density lipoproteins. These fac...
Main Authors: | Stephen J. Nicholls, Stanley L. Hazen |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2009-01-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520306374 |
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