Butyrate Inhibits Colorectal Cancer Cell Proliferation through Autophagy Degradation of β-Catenin Regardless of <i>APC</i> and β-Catenin Mutational Status
Colorectal cancer (CRC) pathogenesis is mainly driven by alterations in WNT signaling, which results in altered transcriptional activity of β-Catenin. Mutations in <i>APC</i> (Adenomatous Polyposis Coli) are reflected in β-Catenin hyperactivation and loss of proliferation control. Certai...
Հիմնական հեղինակներ: | , , , , , , , |
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Ձևաչափ: | Հոդված |
Լեզու: | English |
Հրապարակվել է: |
MDPI AG
2022-05-01
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Շարք: | Biomedicines |
Խորագրեր: | |
Առցանց հասանելիություն: | https://www.mdpi.com/2227-9059/10/5/1131 |