3D Proton Bragg Peak Visualization and Spot Shape Measurement with Polymer Gel Dosimeters
Proton pencil beam scanning is a dynamic beam delivery technique with excellent conformability to the tumor volume. The accuracy of spot size and scanning positions will have a significant effect on the delivered dose distribution. We employed polymer gel dosimeters to measure the spot size and the...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-09-01
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| Series: | Applied Sciences |
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| Online Access: | https://www.mdpi.com/2076-3417/12/19/9839 |
| _version_ | 1797480617097560064 |
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| author | Libing Zhu Manzhou Zhang Xincheng Xiang Xiangang Wang |
| author_facet | Libing Zhu Manzhou Zhang Xincheng Xiang Xiangang Wang |
| author_sort | Libing Zhu |
| collection | DOAJ |
| description | Proton pencil beam scanning is a dynamic beam delivery technique with excellent conformability to the tumor volume. The accuracy of spot size and scanning positions will have a significant effect on the delivered dose distribution. We employed polymer gel dosimeters to measure the spot size and the scanning positions for the Shanghai Advanced Proton Therapy facility (SAPT). Polymer gel dosimeters (MAGAT-f and PAGAT) were utilized to measure the full width at half maximum (FWHM) of the beam spot at various depths on the basis of their MRI readouts. The correlation between the spot FWHM and standard deviation (σ) was analyzed at different depths. The measured Bragg peak range was compared with the Monte Carlo (MC) simulation. Three-dimensional volume rendering of the Bragg peak was reconstructed for the 3D visualization to measure the spot size three-dimensionally. The R<sub>2</sub> dose–response curve was investigated with polymer gel dosimeters. The deviations of the Bragg peak ranging between measurement and simulation were 0.13% and −0.53% for MAGAT-f and PAGAT, respectively. Our results ascertain the feasibility of a polymer gel dosimeter to measure the spot size and positions of a proton pencil beam. |
| first_indexed | 2024-03-09T22:02:39Z |
| format | Article |
| id | doaj.art-7f2a8a6ebc654813a692abe21d6c1263 |
| institution | Directory Open Access Journal |
| issn | 2076-3417 |
| language | English |
| last_indexed | 2024-03-09T22:02:39Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Applied Sciences |
| spelling | doaj.art-7f2a8a6ebc654813a692abe21d6c12632023-11-23T19:46:31ZengMDPI AGApplied Sciences2076-34172022-09-011219983910.3390/app121998393D Proton Bragg Peak Visualization and Spot Shape Measurement with Polymer Gel DosimetersLibing Zhu0Manzhou Zhang1Xincheng Xiang2Xiangang Wang3Institute of Nuclear and New Energy Technology, Tsinghua University, Beijing 100084, ChinaShanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai 201210, ChinaInstitute of Nuclear and New Energy Technology, Tsinghua University, Beijing 100084, ChinaInstitute of Nuclear and New Energy Technology, Tsinghua University, Beijing 100084, ChinaProton pencil beam scanning is a dynamic beam delivery technique with excellent conformability to the tumor volume. The accuracy of spot size and scanning positions will have a significant effect on the delivered dose distribution. We employed polymer gel dosimeters to measure the spot size and the scanning positions for the Shanghai Advanced Proton Therapy facility (SAPT). Polymer gel dosimeters (MAGAT-f and PAGAT) were utilized to measure the full width at half maximum (FWHM) of the beam spot at various depths on the basis of their MRI readouts. The correlation between the spot FWHM and standard deviation (σ) was analyzed at different depths. The measured Bragg peak range was compared with the Monte Carlo (MC) simulation. Three-dimensional volume rendering of the Bragg peak was reconstructed for the 3D visualization to measure the spot size three-dimensionally. The R<sub>2</sub> dose–response curve was investigated with polymer gel dosimeters. The deviations of the Bragg peak ranging between measurement and simulation were 0.13% and −0.53% for MAGAT-f and PAGAT, respectively. Our results ascertain the feasibility of a polymer gel dosimeter to measure the spot size and positions of a proton pencil beam.https://www.mdpi.com/2076-3417/12/19/9839proton pencil beampolymer gel dosimetersspot size3D visualization |
| spellingShingle | Libing Zhu Manzhou Zhang Xincheng Xiang Xiangang Wang 3D Proton Bragg Peak Visualization and Spot Shape Measurement with Polymer Gel Dosimeters Applied Sciences proton pencil beam polymer gel dosimeters spot size 3D visualization |
| title | 3D Proton Bragg Peak Visualization and Spot Shape Measurement with Polymer Gel Dosimeters |
| title_full | 3D Proton Bragg Peak Visualization and Spot Shape Measurement with Polymer Gel Dosimeters |
| title_fullStr | 3D Proton Bragg Peak Visualization and Spot Shape Measurement with Polymer Gel Dosimeters |
| title_full_unstemmed | 3D Proton Bragg Peak Visualization and Spot Shape Measurement with Polymer Gel Dosimeters |
| title_short | 3D Proton Bragg Peak Visualization and Spot Shape Measurement with Polymer Gel Dosimeters |
| title_sort | 3d proton bragg peak visualization and spot shape measurement with polymer gel dosimeters |
| topic | proton pencil beam polymer gel dosimeters spot size 3D visualization |
| url | https://www.mdpi.com/2076-3417/12/19/9839 |
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