Factors predicting general health concerns and atypical behaviours in children with prenatal alcohol exposure and other adverse exposures
BackgroundPrenatal alcohol exposure (PAE) can have significant negative consequences on the health outcomes of children. Children with PAE often experience other prenatal and postnatal adverse exposures. Increased rates of general health concerns and atypical behaviours are seen in both children wit...
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| Format: | Article |
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Frontiers Media S.A.
2023-05-01
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| Series: | Frontiers in Pediatrics |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fped.2023.1146149/full |
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| author | Sarah J. MacEachern Sarah J. MacEachern Sarah J. MacEachern Preeti Kar Preeti Kar Daphne Nakhid Daphne Nakhid Elena Mitevska Christina Tortorelli Nils D. Forkert Nils D. Forkert Nils D. Forkert Catherine Lebel Catherine Lebel Catherine Lebel Carly A. McMorris Carly A. McMorris Carly A. McMorris W. Ben Gibbard W. Ben Gibbard |
| author_facet | Sarah J. MacEachern Sarah J. MacEachern Sarah J. MacEachern Preeti Kar Preeti Kar Daphne Nakhid Daphne Nakhid Elena Mitevska Christina Tortorelli Nils D. Forkert Nils D. Forkert Nils D. Forkert Catherine Lebel Catherine Lebel Catherine Lebel Carly A. McMorris Carly A. McMorris Carly A. McMorris W. Ben Gibbard W. Ben Gibbard |
| author_sort | Sarah J. MacEachern |
| collection | DOAJ |
| description | BackgroundPrenatal alcohol exposure (PAE) can have significant negative consequences on the health outcomes of children. Children with PAE often experience other prenatal and postnatal adverse exposures. Increased rates of general health concerns and atypical behaviours are seen in both children with PAE as well as with other patterns of adverse exposures, although these have not been systematically described. The association between multiple adverse exposures and adverse health concerns and atypical behaviours in children with PAE is unknown.MethodsDemographic information, medical history, adverse exposures, health concerns, and atypical behaviours were collected from children with confirmed PAE (n = 22; 14 males, age range = 7.9–15.9 years) and their caregivers. Support vector machine learning classification models were used to predict the presence of health concerns and atypical behaviours based on adverse exposures. Associations between the sums of adverse exposures, health concerns, and atypical behaviours were examined using correlation analysis.ResultsAll children experienced health concerns, the most common being sensitivity to sensory inputs (64%; 14/22). Similarly, all children engaged in atypical behaviours, with atypical sensory behaviour (50%; 11/22) being the most common. Prenatal alcohol exposure was most important factor for predicting some health concerns and atypical behaviours, and alone and in combination with other factors. Simple associations between adverse exposures could not be identified for many health concerns and atypical behaviours.ConclusionChildren with PAE and other adverse exposures experience high rates of health concerns and atypical behaviours. This study demonstrates the complex effects of multiple adverse exposures on health and behaviour in children. |
| first_indexed | 2024-03-13T09:52:36Z |
| format | Article |
| id | doaj.art-7f2e9f3128df40f9b306319e80e1c2d0 |
| institution | Directory Open Access Journal |
| issn | 2296-2360 |
| language | English |
| last_indexed | 2024-03-13T09:52:36Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pediatrics |
| spelling | doaj.art-7f2e9f3128df40f9b306319e80e1c2d02023-05-24T05:33:38ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602023-05-011110.3389/fped.2023.11461491146149Factors predicting general health concerns and atypical behaviours in children with prenatal alcohol exposure and other adverse exposuresSarah J. MacEachern0Sarah J. MacEachern1Sarah J. MacEachern2Preeti Kar3Preeti Kar4Daphne Nakhid5Daphne Nakhid6Elena Mitevska7Christina Tortorelli8Nils D. Forkert9Nils D. Forkert10Nils D. Forkert11Catherine Lebel12Catherine Lebel13Catherine Lebel14Carly A. McMorris15Carly A. McMorris16Carly A. McMorris17W. Ben Gibbard18W. Ben Gibbard19Department of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB, CanadaAlberta Children’s Hospital Research Institute, University of Calgary, Calgary, AB, CanadaHotchkiss Brain Institute, University of Calgary, Calgary, AB, CanadaAlberta Children’s Hospital Research Institute, University of Calgary, Calgary, AB, CanadaHotchkiss Brain Institute, University of Calgary, Calgary, AB, CanadaAlberta Children’s Hospital Research Institute, University of Calgary, Calgary, AB, CanadaHotchkiss Brain Institute, University of Calgary, Calgary, AB, CanadaCumming School of Medicine, University of Calgary, Calgary, AB, CanadaMount Royal University, Calgary, AB, CanadaAlberta Children’s Hospital Research Institute, University of Calgary, Calgary, AB, CanadaHotchkiss Brain Institute, University of Calgary, Calgary, AB, CanadaDepartment of Radiology, Cumming School of Medicine, University of Calgary, Calgary, AB, CanadaAlberta Children’s Hospital Research Institute, University of Calgary, Calgary, AB, CanadaHotchkiss Brain Institute, University of Calgary, Calgary, AB, CanadaDepartment of Radiology, Cumming School of Medicine, University of Calgary, Calgary, AB, CanadaDepartment of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB, CanadaAlberta Children’s Hospital Research Institute, University of Calgary, Calgary, AB, CanadaWerklund School of Education, University of Calgary, Calgary, AB, CanadaDepartment of Pediatrics, Cumming School of Medicine, University of Calgary, Calgary, AB, CanadaAlberta Children’s Hospital Research Institute, University of Calgary, Calgary, AB, CanadaBackgroundPrenatal alcohol exposure (PAE) can have significant negative consequences on the health outcomes of children. Children with PAE often experience other prenatal and postnatal adverse exposures. Increased rates of general health concerns and atypical behaviours are seen in both children with PAE as well as with other patterns of adverse exposures, although these have not been systematically described. The association between multiple adverse exposures and adverse health concerns and atypical behaviours in children with PAE is unknown.MethodsDemographic information, medical history, adverse exposures, health concerns, and atypical behaviours were collected from children with confirmed PAE (n = 22; 14 males, age range = 7.9–15.9 years) and their caregivers. Support vector machine learning classification models were used to predict the presence of health concerns and atypical behaviours based on adverse exposures. Associations between the sums of adverse exposures, health concerns, and atypical behaviours were examined using correlation analysis.ResultsAll children experienced health concerns, the most common being sensitivity to sensory inputs (64%; 14/22). Similarly, all children engaged in atypical behaviours, with atypical sensory behaviour (50%; 11/22) being the most common. Prenatal alcohol exposure was most important factor for predicting some health concerns and atypical behaviours, and alone and in combination with other factors. Simple associations between adverse exposures could not be identified for many health concerns and atypical behaviours.ConclusionChildren with PAE and other adverse exposures experience high rates of health concerns and atypical behaviours. This study demonstrates the complex effects of multiple adverse exposures on health and behaviour in children.https://www.frontiersin.org/articles/10.3389/fped.2023.1146149/fullpediatricsdevelopmentprenatal alcohol (Ethanol) exposureadverse exposureshealthbehaviour |
| spellingShingle | Sarah J. MacEachern Sarah J. MacEachern Sarah J. MacEachern Preeti Kar Preeti Kar Daphne Nakhid Daphne Nakhid Elena Mitevska Christina Tortorelli Nils D. Forkert Nils D. Forkert Nils D. Forkert Catherine Lebel Catherine Lebel Catherine Lebel Carly A. McMorris Carly A. McMorris Carly A. McMorris W. Ben Gibbard W. Ben Gibbard Factors predicting general health concerns and atypical behaviours in children with prenatal alcohol exposure and other adverse exposures Frontiers in Pediatrics pediatrics development prenatal alcohol (Ethanol) exposure adverse exposures health behaviour |
| title | Factors predicting general health concerns and atypical behaviours in children with prenatal alcohol exposure and other adverse exposures |
| title_full | Factors predicting general health concerns and atypical behaviours in children with prenatal alcohol exposure and other adverse exposures |
| title_fullStr | Factors predicting general health concerns and atypical behaviours in children with prenatal alcohol exposure and other adverse exposures |
| title_full_unstemmed | Factors predicting general health concerns and atypical behaviours in children with prenatal alcohol exposure and other adverse exposures |
| title_short | Factors predicting general health concerns and atypical behaviours in children with prenatal alcohol exposure and other adverse exposures |
| title_sort | factors predicting general health concerns and atypical behaviours in children with prenatal alcohol exposure and other adverse exposures |
| topic | pediatrics development prenatal alcohol (Ethanol) exposure adverse exposures health behaviour |
| url | https://www.frontiersin.org/articles/10.3389/fped.2023.1146149/full |
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