The Characterization of Cardiac Explants Reveals Unique Fibrosis Patterns and a Predominance of CD8+ T Cell Subpopulations in Patients with Chronic Chagas Cardiomyopathy

The Characterization of Cardiac Explants Reveals Unique Fibrosis Patterns and a Predominance of CD8+ T Cell Subpopulations in Patients with Chronic Chagas Cardiomyopathy

Aim: The present study aimed to characterize the histopathological findings and the phenotype of inflammatory cells in the myocardial tissue of patients with end-stage heart failure (ESHF) secondary to CCC in comparison with ESHF secondary to non-Chagas cardiomyopathies (NCC). Methods: A total of 32...

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Main Authors: Martha Lucía Díaz, Fredy A. Delgado, Ruth A Martínez, Mayra Alejandra Jaimes, Luis Eduardo Echeverría, Sergio Alejandro Gómez-Ochoa, Julio César Mantilla-Hernández, Clara Isabel González
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Pathogens
Subjects:
chagas disease
chronic chagas cardiomyopathy
histopathology
immunophenotyping
Online Access:https://www.mdpi.com/2076-0817/11/12/1402

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