Purine Metabolism and Pyrimidine Metabolism Alteration Is a Potential Mechanism of BDE-47-Induced Apoptosis in Marine Rotifer <i>Brachionus plicatilis</i>

Purine Metabolism and Pyrimidine Metabolism Alteration Is a Potential Mechanism of BDE-47-Induced Apoptosis in Marine Rotifer <i>Brachionus plicatilis</i>

This present study was conducted to provide evidence and an explanation for the apoptosis that occurs in the marine rotifer <i>Brachionus plicatilis</i> when facing 2,2′,4,4′-tetrabromodiphenyl ether (BDE-47) stress. Metabolomics analysis showed that aminoacyl-tRNA biosynthesis, valine,...

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Bibliographic Details
Main Authors: Sai Cao, Jiayi Wang, Xinye You, Bin Zhou, You Wang, Zhongyuan Zhou
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:International Journal of Molecular Sciences
Subjects:
purine metabolism
pyrimidine metabolism
reactive oxygen species
DNA damage
apoptosis
BDE-47
Online Access:https://www.mdpi.com/1422-0067/24/16/12726

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