Ion-trap tandem mass spectrometric analysis of Amadori-glycated phosphatidylethanolamine in human plasma with or without diabetes

Ion-trap tandem mass spectrometric analysis of Amadori-glycated phosphatidylethanolamine in human plasma with or without diabetes

Peroxidized phospholipid-mediated cytotoxicity is involved in the pathophysiology of diseases [i.e., an abnormal increase of phosphatidylcholine hydroperoxide (PCOOH) in plasma of type 2 diabetic patients]. The PCOOH accumulation may relate to Amadori-glycated phosphatidylethanolamine (Amadori-PE; d...

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Bibliographic Details
Main Authors: Kiyotaka Nakagawa, Jeong-Ho Oak, Ohki Higuchi, Tsuyoshi Tsuzuki, Shinichi Oikawa, Haruhisa Otani, Masatoshi Mune, Hua Cai, Teruo Miyazawa
Format: Article
Language:English
Published: Elsevier 2005-11-01
Series:Journal of Lipid Research
Subjects:
glycation
QTRAP mass spectrometer
lipid peroxidation
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752032890X

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