Research Progress on Quality Control Methods for Xiaochaihu Preparations
Xiaochaihu (XCH) is a classic Chinese medicine formula. XCH tablet, XCH granule, XCH capsule, and XCH effervescent tablet are included in the Chinese Pharmacopoeia. In this review, the formula and quality standards of XCH preparations at home and abroad were compared. The differences in manufacturin...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-11-01
|
| Series: | Separations |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2297-8739/8/11/199 |
| _version_ | 1797508449296187392 |
|---|---|
| author | Guangzheng Xu Hui Wang Yingqian Deng Keyi Xie Weibo Zhao Xingchu Gong |
| author_facet | Guangzheng Xu Hui Wang Yingqian Deng Keyi Xie Weibo Zhao Xingchu Gong |
| author_sort | Guangzheng Xu |
| collection | DOAJ |
| description | Xiaochaihu (XCH) is a classic Chinese medicine formula. XCH tablet, XCH granule, XCH capsule, and XCH effervescent tablet are included in the Chinese Pharmacopoeia. In this review, the formula and quality standards of XCH preparations at home and abroad were compared. The differences in manufacturing process of XCH preparations are discussed. The progress of research on the qualitative identification, quantitative detection and fingerprint chromatogram/specific chromatogram of XCH preparations was reviewed. The characteristic components of Pinelliae Rhizoma Praeparatum Cum Zingibere Et Alumine and Jujubae Fructus was rarely analyzed for XCH preparations. It is suggested that the specificity of drug quality detection methods should be improved. Considering drug safety and drug efficacy, it is suggested to set the upper and lower limits of the content of saikosaponins. The standards for heavy metals and other limited items for XCH preparations are also suggested to be set. |
| first_indexed | 2024-03-10T05:04:14Z |
| format | Article |
| id | doaj.art-7f3c76fe29594ca1937d66f29ae2980b |
| institution | Directory Open Access Journal |
| issn | 2297-8739 |
| language | English |
| last_indexed | 2024-03-10T05:04:14Z |
| publishDate | 2021-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Separations |
| spelling | doaj.art-7f3c76fe29594ca1937d66f29ae2980b2023-11-23T01:29:43ZengMDPI AGSeparations2297-87392021-11-0181119910.3390/separations8110199Research Progress on Quality Control Methods for Xiaochaihu PreparationsGuangzheng Xu0Hui Wang1Yingqian Deng2Keyi Xie3Weibo Zhao4Xingchu Gong5Pharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, ChinaPharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, ChinaPharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, ChinaPharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, ChinaPharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, ChinaPharmaceutical Informatics Institute, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, ChinaXiaochaihu (XCH) is a classic Chinese medicine formula. XCH tablet, XCH granule, XCH capsule, and XCH effervescent tablet are included in the Chinese Pharmacopoeia. In this review, the formula and quality standards of XCH preparations at home and abroad were compared. The differences in manufacturing process of XCH preparations are discussed. The progress of research on the qualitative identification, quantitative detection and fingerprint chromatogram/specific chromatogram of XCH preparations was reviewed. The characteristic components of Pinelliae Rhizoma Praeparatum Cum Zingibere Et Alumine and Jujubae Fructus was rarely analyzed for XCH preparations. It is suggested that the specificity of drug quality detection methods should be improved. Considering drug safety and drug efficacy, it is suggested to set the upper and lower limits of the content of saikosaponins. The standards for heavy metals and other limited items for XCH preparations are also suggested to be set.https://www.mdpi.com/2297-8739/8/11/199Xiaochaihu (XCH) formulapreparationsquality controlstandard |
| spellingShingle | Guangzheng Xu Hui Wang Yingqian Deng Keyi Xie Weibo Zhao Xingchu Gong Research Progress on Quality Control Methods for Xiaochaihu Preparations Separations Xiaochaihu (XCH) formula preparations quality control standard |
| title | Research Progress on Quality Control Methods for Xiaochaihu Preparations |
| title_full | Research Progress on Quality Control Methods for Xiaochaihu Preparations |
| title_fullStr | Research Progress on Quality Control Methods for Xiaochaihu Preparations |
| title_full_unstemmed | Research Progress on Quality Control Methods for Xiaochaihu Preparations |
| title_short | Research Progress on Quality Control Methods for Xiaochaihu Preparations |
| title_sort | research progress on quality control methods for xiaochaihu preparations |
| topic | Xiaochaihu (XCH) formula preparations quality control standard |
| url | https://www.mdpi.com/2297-8739/8/11/199 |
| work_keys_str_mv | AT guangzhengxu researchprogressonqualitycontrolmethodsforxiaochaihupreparations AT huiwang researchprogressonqualitycontrolmethodsforxiaochaihupreparations AT yingqiandeng researchprogressonqualitycontrolmethodsforxiaochaihupreparations AT keyixie researchprogressonqualitycontrolmethodsforxiaochaihupreparations AT weibozhao researchprogressonqualitycontrolmethodsforxiaochaihupreparations AT xingchugong researchprogressonqualitycontrolmethodsforxiaochaihupreparations |