Programmable System of Cas13-Mediated RNA Modification and Its Biological and Biomedical Applications

Programmable System of Cas13-Mediated RNA Modification and Its Biological and Biomedical Applications

Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas13 has drawn broad interest to control gene expression and cell fate at the RNA level in general. Apart from RNA interference mediated by its endonuclease activity, the nuclease-deactivated form of Cas13 further provides a versati...

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Bibliographic Details
Main Authors: Tian Tang, Yingli Han, Yuran Wang, He Huang, Pengxu Qian
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
CRISPR-Cas13 system
RNA modification
epigenetic editing
CRISPR
cell biology
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.677587/full

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