Senecavirus A Entry Into Host Cells Is Dependent on the Cholesterol-Mediated Endocytic Pathway

Senecavirus A Entry Into Host Cells Is Dependent on the Cholesterol-Mediated Endocytic Pathway

Senecavirus A (SVA), an important member of the Picornaviridae family, causes vesicular disease in pigs. Here, we generated an EGFP-expressing recombinant SVA re-SVA-EGFP, which exhibited similar growth kinetics to its parental virus. The reporter SVA was used to study the role of pig ANTXR1 (pANTXR...

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Bibliographic Details
Main Authors: Meiyu Jia, Mingxia Sun, Yan-Dong Tang, Yu-Yuan Zhang, Haiwei Wang, Xuehui Cai, Fandan Meng
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Veterinary Science
Subjects:
SVA
reporter virus
viral entry
pig ANTXR1
cholesterol
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2022.840655/full

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https://www.frontiersin.org/articles/10.3389/fvets.2022.840655/full

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