Thermoreversible Gels Based on Chitosan Copolymers as “Intelligent” Drug Delivery System with Prolonged Action for Intramuscular Injection

Thermoreversible Gels Based on Chitosan Copolymers as “Intelligent” Drug Delivery System with Prolonged Action for Intramuscular Injection

Thermosensitive gels based on copolymers (PEG–chitosan, chitosan–polyethylenimine, chitosan–arginine and glycol–chitosan–spermine) are presented as promising polycations for the formation of DNA polyplexes and the potential for the development of drugs with prolonged release (up to 30 days). Being i...

Full description

Bibliographic Details
Main Authors: Igor D. Zlotnikov, Stanislav M. Malashkeevich, Natalia G. Belogurova, Elena V. Kudryashova
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Pharmaceutics
Subjects:
polycationic polymer
thermoreversible gel
gene delivery
DNA polyplex
flow cytometry
FTIR
Online Access:https://www.mdpi.com/1999-4923/15/5/1478

Similar Items

Similar Items