Natural killer cell signal integration balances synapse symmetry and migration.
Natural killer (NK) cells discern the health of other cells by recognising the balance of activating and inhibitory ligands expressed by each target cell. However, how the integration of activating and inhibitory signals relates to formation of the NK cell immune synapse remains a central question i...
Main Authors: | Fiona J Culley, Matthew Johnson, J Henry Evans, Sunil Kumar, Rupert Crilly, Juan Casasbuenas, Tim Schnyder, Maryam Mehrabi, Mahendra P Deonarain, Dmitry S Ushakov, Veronique Braud, Günter Roth, Roland Brock, Karsten Köhler, Daniel M Davis |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2009-07-01
|
Series: | PLoS Biology |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19636352/?tool=EBI |
Similar Items
-
Reciprocal regulation of human natural killer cells and macrophages associated with distinct immune synapses.
by: Nedvetzki, S, et al.
Published: (2007) -
The role of the cytoskeleton and protein size in assembly of the human natural killer cell immune synapse
by: McCann, F, et al.
Published: (2003) -
Opposing effects of PKCtheta and WASp on symmetry breaking and relocation of the immunological synapse.
by: Sims, T, et al.
Published: (2007) -
Intercellular transfer and supramolecular organization of human leukocyte antigen C at inhibitory natural killer cell immune synapses.
by: Carlin, L, et al.
Published: (2001) -
Natural killer cell lytic granule secretion occurs through a pervasive actin network at the immune synapse.
by: Gregory D Rak, et al.
Published: (2011-09-01)