EMT alterations in the solute carrier landscape uncover SLC22A10/A15 imposed vulnerabilities in pancreatic cancer

EMT alterations in the solute carrier landscape uncover SLC22A10/A15 imposed vulnerabilities in pancreatic cancer

Summary: The involvement of membrane-bound solute carriers (SLCs) in neoplastic transdifferentiation processes is poorly defined. Here, we examined changes in the SLC landscape during epithelial-mesenchymal transition (EMT) of pancreatic cancer cells. We show that two SLCs from the organic anion/cat...

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Bibliographic Details
Main Authors: Debasis Nayak, Brenna Weadick, Avinash K. Persaud, Radhika Raj, Reena Shakya, Junan Li, Moray J. Campbell, Rajgopal Govindarajan
Format: Article
Language:English
Published: Elsevier 2022-05-01
Series:iScience
Subjects:
Biological sciences
Immunology
Cancer
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222004631

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