Nucleic Acid Aptamers Targeting Epigenetic Regulators: An Innovative Therapeutic Option

Nucleic Acid Aptamers Targeting Epigenetic Regulators: An Innovative Therapeutic Option

Epigenetic mechanisms include DNA methylation, posttranslational modifications of histones, chromatin remodeling factors, and post transcriptional gene regulation by noncoding RNAs. All together, these processes regulate gene expression by changing chromatin organization and DNA accessibility. Targe...

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Bibliographic Details
Main Authors:	Silvia Catuogno, Carla Lucia Esposito, Paola Ungaro, Vittorio de Franciscis
Format:	Article
Language:	English
Published:	MDPI AG 2018-08-01
Series:	Pharmaceuticals
Subjects:	epigenetics aptamers targeted therapy
Online Access:	http://www.mdpi.com/1424-8247/11/3/79

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