Radiation-Induced Heart Diseases: Protective Effects of Natural Products

Cardiovascular diseases (CVDs) account for the majority of deaths worldwide. Radiation-induced heart diseases (RIHD) is one of the side effects following exposure to ionizing radiation (IR). Exposure could be from various forms such as diagnostic imaging, radiotherapy for cancer treatment, as well a...

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Main Authors: Ahmed Eleojo Musa, Dheyauldeen Shabeeb
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1010-660X/55/5/126
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author Ahmed Eleojo Musa
Dheyauldeen Shabeeb
author_facet Ahmed Eleojo Musa
Dheyauldeen Shabeeb
author_sort Ahmed Eleojo Musa
collection DOAJ
description Cardiovascular diseases (CVDs) account for the majority of deaths worldwide. Radiation-induced heart diseases (RIHD) is one of the side effects following exposure to ionizing radiation (IR). Exposure could be from various forms such as diagnostic imaging, radiotherapy for cancer treatment, as well as nuclear disasters and nuclear accidents. RIHD is mostly observed after radiotherapy for thoracic malignancies, especially left breast cancer. RIHD may affect the supply of blood to heart muscles, leading to an increase in the risk of heart attacks to irradiated persons. Due to its dose-limiting consequence, RIHD has a negative effect on the therapeutic efficacy of radiotherapy. Several methods have been proposed for protection against RIHD. In this paper, we review the use of natural products, which have shown promising results for protection against RIHD.
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spelling doaj.art-7f4c1ed344cc4db6ae9fc6283cc813d22023-09-03T00:33:11ZengMDPI AGMedicina1010-660X2019-05-0155512610.3390/medicina55050126medicina55050126Radiation-Induced Heart Diseases: Protective Effects of Natural ProductsAhmed Eleojo Musa0Dheyauldeen Shabeeb1Department of Medical Physics, Tehran University of Medical Sciences (TUMS), International Campus, Tehran 1416753955, IranDepartment of Physiology, College of Medicine, University of Misan, Misan 62010, IraqCardiovascular diseases (CVDs) account for the majority of deaths worldwide. Radiation-induced heart diseases (RIHD) is one of the side effects following exposure to ionizing radiation (IR). Exposure could be from various forms such as diagnostic imaging, radiotherapy for cancer treatment, as well as nuclear disasters and nuclear accidents. RIHD is mostly observed after radiotherapy for thoracic malignancies, especially left breast cancer. RIHD may affect the supply of blood to heart muscles, leading to an increase in the risk of heart attacks to irradiated persons. Due to its dose-limiting consequence, RIHD has a negative effect on the therapeutic efficacy of radiotherapy. Several methods have been proposed for protection against RIHD. In this paper, we review the use of natural products, which have shown promising results for protection against RIHD.https://www.mdpi.com/1010-660X/55/5/126ionizing radiationheart diseaseradiotherapynatural productscancerinflammation
spellingShingle Ahmed Eleojo Musa
Dheyauldeen Shabeeb
Radiation-Induced Heart Diseases: Protective Effects of Natural Products
Medicina
ionizing radiation
heart disease
radiotherapy
natural products
cancer
inflammation
title Radiation-Induced Heart Diseases: Protective Effects of Natural Products
title_full Radiation-Induced Heart Diseases: Protective Effects of Natural Products
title_fullStr Radiation-Induced Heart Diseases: Protective Effects of Natural Products
title_full_unstemmed Radiation-Induced Heart Diseases: Protective Effects of Natural Products
title_short Radiation-Induced Heart Diseases: Protective Effects of Natural Products
title_sort radiation induced heart diseases protective effects of natural products
topic ionizing radiation
heart disease
radiotherapy
natural products
cancer
inflammation
url https://www.mdpi.com/1010-660X/55/5/126
work_keys_str_mv AT ahmedeleojomusa radiationinducedheartdiseasesprotectiveeffectsofnaturalproducts
AT dheyauldeenshabeeb radiationinducedheartdiseasesprotectiveeffectsofnaturalproducts