Is There a Relationship Between Use of Anti-Vascular Endothelial Growth Factor Agents and Atrophic Changes in Age-Related Macular Degeneration Patients?

Choroidal neovascularization due to age-related macular degeneration (AMD) is currently treated successfully with anti-vascular endothelial growth factor (VEGF) intravitreal agents. Emerging evidence suggests that anti-VEGF treatment may potentially increase development of geographic atrophy. Howeve...

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Bibliographic Details
Main Authors: Süleyman Kaynak, Mahmut Kaya, Derya Kaya
Format: Article
Language:English
Published: Galenos Yayinevi 2018-04-01
Series:Türk Oftalmoloji Dergisi
Subjects:
Online Access:http://www.oftalmoloji.org/archives/archive-detail/article-preview/s-there-a-relationship-between-use-of-anti-vascula/17059
Description
Summary:Choroidal neovascularization due to age-related macular degeneration (AMD) is currently treated successfully with anti-vascular endothelial growth factor (VEGF) intravitreal agents. Emerging evidence suggests that anti-VEGF treatment may potentially increase development of geographic atrophy. However, there is not yet direct proof of a causal relationship between geographic atrophy and use of anti-VEGF agents in neovaskuler AMD. The aim of this review is to discuss the evidence concerning the association between anti-VEGF therapy and progression of geographic atrophy.
ISSN:1300-0659
2147-2661