The role and utility of cholangioscopy for diagnosing indeterminate biliary strictures
Biliary strictures are considered indeterminate when evaluation with imaging and standard tissue sampling during endoscopic retrograde cholangiopancreatography (ERCP) are non-diagnostic. Standard tissue sampling techniques include cytologic brushings, with or without fluorescence in situ hybridizati...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Society of Gastrointestinal Intervention
2017-03-01
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| Series: | Gastrointestinal Intervention |
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| Online Access: | https://doi.org/10.18528/gii160035 |
| _version_ | 1828489675171430400 |
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| author | Adarsh M. Thaker V. Raman Muthusamy |
| author_facet | Adarsh M. Thaker V. Raman Muthusamy |
| author_sort | Adarsh M. Thaker |
| collection | DOAJ |
| description | Biliary strictures are considered indeterminate when evaluation with imaging and standard tissue sampling during endoscopic retrograde cholangiopancreatography (ERCP) are non-diagnostic. Standard tissue sampling techniques include cytologic brushings, with or without fluorescence in situ hybridization (FISH), and endoscopic intraductal biopsies. These strictures are often clinically suspicious for malignancy. The management of these patients can vary substantially and relies on an accurate diagnosis of the lesion. Unfortunately, despite numerous modalities, the sensitivity of existing tissue sampling techniques remains low and can lead to delays in diagnosis and the need for additional procedures. Cholangioscopy has emerged as a means to visually inspect and obtain image-guided biopsies of the lesion in question, with improved sensitivity as well as a high specificity and accuracy for diagnosing the etiology of indeterminate biliary strictures. The types of cholangioscopy systems and a summary of the pertinent literature are discussed in this review. |
| first_indexed | 2024-12-11T10:30:10Z |
| format | Article |
| id | doaj.art-7f50e8e25a3b43cab82c1eea6998c85c |
| institution | Directory Open Access Journal |
| issn | 2213-1795 |
| language | English |
| last_indexed | 2024-12-11T10:30:10Z |
| publishDate | 2017-03-01 |
| publisher | Society of Gastrointestinal Intervention |
| record_format | Article |
| series | Gastrointestinal Intervention |
| spelling | doaj.art-7f50e8e25a3b43cab82c1eea6998c85c2022-12-22T01:10:58ZengSociety of Gastrointestinal InterventionGastrointestinal Intervention2213-17952017-03-01612810.18528/gii160035gii160035The role and utility of cholangioscopy for diagnosing indeterminate biliary stricturesAdarsh M. Thaker0V. Raman Muthusamy1Division of Digestive Diseases, David Geffen School of Medicine at UCLA, Los Angeles, CA, USADivision of Digestive Diseases, David Geffen School of Medicine at UCLA, Los Angeles, CA, USABiliary strictures are considered indeterminate when evaluation with imaging and standard tissue sampling during endoscopic retrograde cholangiopancreatography (ERCP) are non-diagnostic. Standard tissue sampling techniques include cytologic brushings, with or without fluorescence in situ hybridization (FISH), and endoscopic intraductal biopsies. These strictures are often clinically suspicious for malignancy. The management of these patients can vary substantially and relies on an accurate diagnosis of the lesion. Unfortunately, despite numerous modalities, the sensitivity of existing tissue sampling techniques remains low and can lead to delays in diagnosis and the need for additional procedures. Cholangioscopy has emerged as a means to visually inspect and obtain image-guided biopsies of the lesion in question, with improved sensitivity as well as a high specificity and accuracy for diagnosing the etiology of indeterminate biliary strictures. The types of cholangioscopy systems and a summary of the pertinent literature are discussed in this review.https://doi.org/10.18528/gii160035Bile duct diseasesCholangiocarcinomaCholangioscopyCholangitis, sclerosing |
| spellingShingle | Adarsh M. Thaker V. Raman Muthusamy The role and utility of cholangioscopy for diagnosing indeterminate biliary strictures Gastrointestinal Intervention Bile duct diseases Cholangiocarcinoma Cholangioscopy Cholangitis, sclerosing |
| title | The role and utility of cholangioscopy for diagnosing indeterminate biliary strictures |
| title_full | The role and utility of cholangioscopy for diagnosing indeterminate biliary strictures |
| title_fullStr | The role and utility of cholangioscopy for diagnosing indeterminate biliary strictures |
| title_full_unstemmed | The role and utility of cholangioscopy for diagnosing indeterminate biliary strictures |
| title_short | The role and utility of cholangioscopy for diagnosing indeterminate biliary strictures |
| title_sort | role and utility of cholangioscopy for diagnosing indeterminate biliary strictures |
| topic | Bile duct diseases Cholangiocarcinoma Cholangioscopy Cholangitis, sclerosing |
| url | https://doi.org/10.18528/gii160035 |
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