Systemic insulin sensitivity is regulated by GPS2 inhibition of AKT ubiquitination and activation in adipose tissue

Systemic insulin sensitivity is regulated by GPS2 inhibition of AKT ubiquitination and activation in adipose tissue

Objective: Insulin signaling plays a unique role in the regulation of energy homeostasis and the impairment of insulin action is associated with altered lipid metabolism, obesity, and Type 2 Diabetes. The main aim of this study was to provide further insight into the regulatory mechanisms governing...

Full description

Bibliographic Details
Main Authors: Carly T. Cederquist, Claudia Lentucci, Camila Martinez-Calejman, Vanessa Hayashi, Joseph Orofino, David Guertin, Susan K. Fried, Mi-Jeong Lee, M. Dafne Cardamone, Valentina Perissi
Format: Article
Language:English
Published: Elsevier 2017-01-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877816302101

Similar Items

Similar Items