Identification of rare X-linked neuroligin variants by massively parallel sequencing in males with autism spectrum disorder

Identification of rare X-linked neuroligin variants by massively parallel sequencing in males with autism spectrum disorder

<p>Abstract</p> <p>Background</p> <p>Autism spectrum disorder (ASD) is highly heritable, but the genetic risk factors for it remain largely unknown. Although structural variants with large effect sizes may explain up to 15% ASD, genome-wide association studies have fail...

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Bibliographic Details
Main Authors: Steinberg Karyn, Ramachandran Dhanya, Patel Viren C, Shetty Amol C, Cutler David J, Zwick Michael E
Format: Article
Language:English
Published: BMC 2012-09-01
Series:Molecular Autism
Subjects:
Autism spectrum disorder
Massively parallel DNA sequencing
Rare variation
Evolutionary conservation
Online Access:http://www.molecularautism.com/content/3/1/8

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