Field and Molecular Epidemiology: How Viral Sequencing Changed Transmission Inferences in the First Portuguese SARS-CoV-2 Infection Cluster
Field epidemiology and viral sequencing provide a comprehensive characterization of transmission chains and allow a better identification of superspreading events. However, very few examples have been presented to date during the COVID-19 pandemic. We studied the first COVID-19 cluster detected in P...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-06-01
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| Series: | Viruses |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1999-4915/13/6/1116 |
| _version_ | 1827690146178269184 |
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| author | Nicole Pedro Veronica Fernandes Bruno Cavadas João Tiago Guimarães Henrique Barros Margarida Tavares Luisa Pereira |
| author_facet | Nicole Pedro Veronica Fernandes Bruno Cavadas João Tiago Guimarães Henrique Barros Margarida Tavares Luisa Pereira |
| author_sort | Nicole Pedro |
| collection | DOAJ |
| description | Field epidemiology and viral sequencing provide a comprehensive characterization of transmission chains and allow a better identification of superspreading events. However, very few examples have been presented to date during the COVID-19 pandemic. We studied the first COVID-19 cluster detected in Portugal (59 individuals involved amongst extended family and work environments), following the return of four related individuals from work trips to Italy. The first patient to introduce the virus would be misidentified following the traditional field inquiry alone, as shown by the viral sequencing in isolates from 23 individuals. The results also pointed out family, and not work environment, as the primary mode of transmission. |
| first_indexed | 2024-03-10T10:32:19Z |
| format | Article |
| id | doaj.art-7f5957152e0242fd907878c7dc7bed06 |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-10T10:32:19Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-7f5957152e0242fd907878c7dc7bed062023-11-21T23:31:44ZengMDPI AGViruses1999-49152021-06-01136111610.3390/v13061116Field and Molecular Epidemiology: How Viral Sequencing Changed Transmission Inferences in the First Portuguese SARS-CoV-2 Infection ClusterNicole Pedro0Veronica Fernandes1Bruno Cavadas2João Tiago Guimarães3Henrique Barros4Margarida Tavares5Luisa Pereira6i3S, Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugali3S, Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, Portugali3S, Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, PortugalCHUSJ, Centro Hospitalar Universitário S. João, 4200-319 Porto, PortugalFMUP, Faculdade de Medicina da Universidade do Porto, 4200-319 Porto, PortugalCHUSJ, Centro Hospitalar Universitário S. João, 4200-319 Porto, Portugali3S, Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 4200-135 Porto, PortugalField epidemiology and viral sequencing provide a comprehensive characterization of transmission chains and allow a better identification of superspreading events. However, very few examples have been presented to date during the COVID-19 pandemic. We studied the first COVID-19 cluster detected in Portugal (59 individuals involved amongst extended family and work environments), following the return of four related individuals from work trips to Italy. The first patient to introduce the virus would be misidentified following the traditional field inquiry alone, as shown by the viral sequencing in isolates from 23 individuals. The results also pointed out family, and not work environment, as the primary mode of transmission.https://www.mdpi.com/1999-4915/13/6/1116COVID-19infection clusterviral sequencingepidemiological surveyfamily versus work environment |
| spellingShingle | Nicole Pedro Veronica Fernandes Bruno Cavadas João Tiago Guimarães Henrique Barros Margarida Tavares Luisa Pereira Field and Molecular Epidemiology: How Viral Sequencing Changed Transmission Inferences in the First Portuguese SARS-CoV-2 Infection Cluster Viruses COVID-19 infection cluster viral sequencing epidemiological survey family versus work environment |
| title | Field and Molecular Epidemiology: How Viral Sequencing Changed Transmission Inferences in the First Portuguese SARS-CoV-2 Infection Cluster |
| title_full | Field and Molecular Epidemiology: How Viral Sequencing Changed Transmission Inferences in the First Portuguese SARS-CoV-2 Infection Cluster |
| title_fullStr | Field and Molecular Epidemiology: How Viral Sequencing Changed Transmission Inferences in the First Portuguese SARS-CoV-2 Infection Cluster |
| title_full_unstemmed | Field and Molecular Epidemiology: How Viral Sequencing Changed Transmission Inferences in the First Portuguese SARS-CoV-2 Infection Cluster |
| title_short | Field and Molecular Epidemiology: How Viral Sequencing Changed Transmission Inferences in the First Portuguese SARS-CoV-2 Infection Cluster |
| title_sort | field and molecular epidemiology how viral sequencing changed transmission inferences in the first portuguese sars cov 2 infection cluster |
| topic | COVID-19 infection cluster viral sequencing epidemiological survey family versus work environment |
| url | https://www.mdpi.com/1999-4915/13/6/1116 |
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