A case of subacute cutaneous lupus erythematosus as a result of ranibizumab (Lucentis) treatment
Cutaneous lupus erythematosus is a previously undiagnosed side-effect of ranibizumab. Here, we present a case of an 82-year-old female Caucasian patient with wet age-related macular degeneration. Following a single intraocular injection of Lucentis (ranibizumab), she developed a subacute cutaneous l...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2013-01-01
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| Series: | Indian Journal of Ophthalmology |
| Subjects: | |
| Online Access: | http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=12;spage=752;epage=754;aulast=Andric |
| _version_ | 1811308505240436736 |
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| author | Marko Andric Shreya Dixit Dana Robaei Rosemary Watchorn Nitin Verma |
| author_facet | Marko Andric Shreya Dixit Dana Robaei Rosemary Watchorn Nitin Verma |
| author_sort | Marko Andric |
| collection | DOAJ |
| description | Cutaneous lupus erythematosus is a previously undiagnosed side-effect of ranibizumab. Here, we present a case of an 82-year-old female Caucasian patient with wet age-related macular degeneration. Following a single intraocular injection of Lucentis (ranibizumab), she developed a subacute cutaneous lupus erythematosus which, with treatment, took nearly 12 months to resolve. This shows that cutaneous lupus erythematosus is a potential side-effect of many medications, including ranibizumab, as in our case and, in an aging population where polypharmacy is a growing reality, clinicians should be aware of how to diagnose and best manage such cases. |
| first_indexed | 2024-04-13T09:24:29Z |
| format | Article |
| id | doaj.art-7f5a38fefe834eb2bd28ae7e6f2184b2 |
| institution | Directory Open Access Journal |
| issn | 0301-4738 1998-3689 |
| language | English |
| last_indexed | 2024-04-13T09:24:29Z |
| publishDate | 2013-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Ophthalmology |
| spelling | doaj.art-7f5a38fefe834eb2bd28ae7e6f2184b22022-12-22T02:52:30ZengWolters Kluwer Medknow PublicationsIndian Journal of Ophthalmology0301-47381998-36892013-01-01611275275410.4103/0301-4738.121133A case of subacute cutaneous lupus erythematosus as a result of ranibizumab (Lucentis) treatmentMarko AndricShreya DixitDana RobaeiRosemary WatchornNitin VermaCutaneous lupus erythematosus is a previously undiagnosed side-effect of ranibizumab. Here, we present a case of an 82-year-old female Caucasian patient with wet age-related macular degeneration. Following a single intraocular injection of Lucentis (ranibizumab), she developed a subacute cutaneous lupus erythematosus which, with treatment, took nearly 12 months to resolve. This shows that cutaneous lupus erythematosus is a potential side-effect of many medications, including ranibizumab, as in our case and, in an aging population where polypharmacy is a growing reality, clinicians should be aware of how to diagnose and best manage such cases.http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=12;spage=752;epage=754;aulast=AndricAmblyopianasolacrimal duct obstructionprobingDuane syndromeesotropiastrabismusBevacizumabmitochondrial functionmicrovascular endothelial cellsneurosensory retinal cellsretinal pigment epithelial cellstissue cultureClinical donor tissue gradingdeath to enucleation timedeath to preservation timeeye bank specular microscopyoptimizing donor tissue utilizationDCRendodiathermy bipolar probenasolacrimal duct obstructionrecanalizeAge-related macular degenerationcarotenoidscross-sectional studiesluteinChildrenGDx variable corneal compensationIndiannormalretinal nerve fiber layer thicknessBiological amniotic membrane5-fluorouracilretinatrabeculectomyClinical featurescomplicationsetiologyretinal vasculitisThailandColoboma of the choroidcoloboma optic discindo cyanine green angiographyvascular patternAphakiainadequate capsular supportpediatric aphakiasecondary intraocular lens implantationsteel suturetrans-scleral fixationvanadium steelDrug reactiondrug-inducedranibizumabsubacute cutaneous lupus erythematosus |
| spellingShingle | Marko Andric Shreya Dixit Dana Robaei Rosemary Watchorn Nitin Verma A case of subacute cutaneous lupus erythematosus as a result of ranibizumab (Lucentis) treatment Indian Journal of Ophthalmology Amblyopia nasolacrimal duct obstruction probing Duane syndrome esotropia strabismus Bevacizumab mitochondrial function microvascular endothelial cells neurosensory retinal cells retinal pigment epithelial cells tissue culture Clinical donor tissue grading death to enucleation time death to preservation time eye bank specular microscopy optimizing donor tissue utilization DCR endodiathermy bipolar probe nasolacrimal duct obstruction recanalize Age-related macular degeneration carotenoids cross-sectional studies lutein Children GDx variable corneal compensation Indian normal retinal nerve fiber layer thickness Biological amniotic membrane 5-fluorouracil retina trabeculectomy Clinical features complications etiology retinal vasculitis Thailand Coloboma of the choroid coloboma optic disc indo cyanine green angiography vascular pattern Aphakia inadequate capsular support pediatric aphakia secondary intraocular lens implantation steel suture trans-scleral fixation vanadium steel Drug reaction drug-induced ranibizumab subacute cutaneous lupus erythematosus |
| title | A case of subacute cutaneous lupus erythematosus as a result of ranibizumab (Lucentis) treatment |
| title_full | A case of subacute cutaneous lupus erythematosus as a result of ranibizumab (Lucentis) treatment |
| title_fullStr | A case of subacute cutaneous lupus erythematosus as a result of ranibizumab (Lucentis) treatment |
| title_full_unstemmed | A case of subacute cutaneous lupus erythematosus as a result of ranibizumab (Lucentis) treatment |
| title_short | A case of subacute cutaneous lupus erythematosus as a result of ranibizumab (Lucentis) treatment |
| title_sort | case of subacute cutaneous lupus erythematosus as a result of ranibizumab lucentis treatment |
| topic | Amblyopia nasolacrimal duct obstruction probing Duane syndrome esotropia strabismus Bevacizumab mitochondrial function microvascular endothelial cells neurosensory retinal cells retinal pigment epithelial cells tissue culture Clinical donor tissue grading death to enucleation time death to preservation time eye bank specular microscopy optimizing donor tissue utilization DCR endodiathermy bipolar probe nasolacrimal duct obstruction recanalize Age-related macular degeneration carotenoids cross-sectional studies lutein Children GDx variable corneal compensation Indian normal retinal nerve fiber layer thickness Biological amniotic membrane 5-fluorouracil retina trabeculectomy Clinical features complications etiology retinal vasculitis Thailand Coloboma of the choroid coloboma optic disc indo cyanine green angiography vascular pattern Aphakia inadequate capsular support pediatric aphakia secondary intraocular lens implantation steel suture trans-scleral fixation vanadium steel Drug reaction drug-induced ranibizumab subacute cutaneous lupus erythematosus |
| url | http://www.ijo.in/article.asp?issn=0301-4738;year=2013;volume=61;issue=12;spage=752;epage=754;aulast=Andric |
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