Toward the Commercialization of Carbon Nanotube Field Effect Transistor Biosensors
The development of biosensors based on field-effect transistors (FETs) using atomically thick carbon nanotubes (CNTs) as a channel material has the potential to revolutionize the related field due to their small size, high sensitivity, label-free detection, and real-time monitoring capabilities. Des...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-02-01
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| Series: | Biosensors |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-6374/13/3/326 |
| _version_ | 1827751021344980992 |
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| author | Zhongyu Li Mengmeng Xiao Chuanhong Jin Zhiyong Zhang |
| author_facet | Zhongyu Li Mengmeng Xiao Chuanhong Jin Zhiyong Zhang |
| author_sort | Zhongyu Li |
| collection | DOAJ |
| description | The development of biosensors based on field-effect transistors (FETs) using atomically thick carbon nanotubes (CNTs) as a channel material has the potential to revolutionize the related field due to their small size, high sensitivity, label-free detection, and real-time monitoring capabilities. Despite extensive research efforts to improve the sensitivity, selectivity, and practicality of CNT FET-based biosensors, their commercialization has not yet been achieved due to the non-uniform and unstable device performance, difficulties in their fabrication, the immaturity of sensor packaging processes, and a lack of reliable modification methods. This review article focuses on the practical applications of CNT-based FET biosensors for the detection of ultra-low concentrations of biologically relevant molecules. We discuss the various factors that affect the sensors’ performance in terms of materials, device architecture, and sensor packaging, highlighting the need for a robust commercial process that prioritizes product performance. Additionally, we review recent advances in the application of CNT FET biosensors for the ultra-sensitive detection of various biomarkers. Finally, we examine the key obstacles that currently hinder the large-scale deployment of these biosensors, aiming to identify the challenges that must be addressed for the future industrialization of CNT FET sensors. |
| first_indexed | 2024-03-11T06:51:40Z |
| format | Article |
| id | doaj.art-7f5be6b207614ed98c0c1b4bfbe096f1 |
| institution | Directory Open Access Journal |
| issn | 2079-6374 |
| language | English |
| last_indexed | 2024-03-11T06:51:40Z |
| publishDate | 2023-02-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biosensors |
| spelling | doaj.art-7f5be6b207614ed98c0c1b4bfbe096f12023-11-17T09:53:47ZengMDPI AGBiosensors2079-63742023-02-0113332610.3390/bios13030326Toward the Commercialization of Carbon Nanotube Field Effect Transistor BiosensorsZhongyu Li0Mengmeng Xiao1Chuanhong Jin2Zhiyong Zhang3Hunan Institute of Advanced Sensing and Information Technology, Xiangtan University, Xiangtan 411105, ChinaHunan Institute of Advanced Sensing and Information Technology, Xiangtan University, Xiangtan 411105, ChinaHunan Institute of Advanced Sensing and Information Technology, Xiangtan University, Xiangtan 411105, ChinaHunan Institute of Advanced Sensing and Information Technology, Xiangtan University, Xiangtan 411105, ChinaThe development of biosensors based on field-effect transistors (FETs) using atomically thick carbon nanotubes (CNTs) as a channel material has the potential to revolutionize the related field due to their small size, high sensitivity, label-free detection, and real-time monitoring capabilities. Despite extensive research efforts to improve the sensitivity, selectivity, and practicality of CNT FET-based biosensors, their commercialization has not yet been achieved due to the non-uniform and unstable device performance, difficulties in their fabrication, the immaturity of sensor packaging processes, and a lack of reliable modification methods. This review article focuses on the practical applications of CNT-based FET biosensors for the detection of ultra-low concentrations of biologically relevant molecules. We discuss the various factors that affect the sensors’ performance in terms of materials, device architecture, and sensor packaging, highlighting the need for a robust commercial process that prioritizes product performance. Additionally, we review recent advances in the application of CNT FET biosensors for the ultra-sensitive detection of various biomarkers. Finally, we examine the key obstacles that currently hinder the large-scale deployment of these biosensors, aiming to identify the challenges that must be addressed for the future industrialization of CNT FET sensors.https://www.mdpi.com/2079-6374/13/3/326field effect transistorcarbon nanotubebiosensorscommercialization |
| spellingShingle | Zhongyu Li Mengmeng Xiao Chuanhong Jin Zhiyong Zhang Toward the Commercialization of Carbon Nanotube Field Effect Transistor Biosensors Biosensors field effect transistor carbon nanotube biosensors commercialization |
| title | Toward the Commercialization of Carbon Nanotube Field Effect Transistor Biosensors |
| title_full | Toward the Commercialization of Carbon Nanotube Field Effect Transistor Biosensors |
| title_fullStr | Toward the Commercialization of Carbon Nanotube Field Effect Transistor Biosensors |
| title_full_unstemmed | Toward the Commercialization of Carbon Nanotube Field Effect Transistor Biosensors |
| title_short | Toward the Commercialization of Carbon Nanotube Field Effect Transistor Biosensors |
| title_sort | toward the commercialization of carbon nanotube field effect transistor biosensors |
| topic | field effect transistor carbon nanotube biosensors commercialization |
| url | https://www.mdpi.com/2079-6374/13/3/326 |
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