Renal cell carcinoma in children and adolescence: Our experience
Background: Literature on renal cell carcinoma (RCC) in children is lacking. Occasional case report has been mentioned. Aims and objective of our study are to evaluate the clinical presentation and outcome in children with RCC. Patients and Methods: Records of 11 children and adolescence, from Janua...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2014-01-01
|
| Series: | African Journal of Paediatric Surgery |
| Subjects: | |
| Online Access: | http://www.afrjpaedsurg.org/article.asp?issn=0189-6725;year=2014;volume=11;issue=2;spage=101;epage=104;aulast=Kumar |
| _version_ | 1818936972559777792 |
|---|---|
| author | Suresh Kumar Pramod Sharma Jittendra Pratap Punit Tiwari Malay K. Bera Anup K. Kundu |
| author_facet | Suresh Kumar Pramod Sharma Jittendra Pratap Punit Tiwari Malay K. Bera Anup K. Kundu |
| author_sort | Suresh Kumar |
| collection | DOAJ |
| description | Background: Literature on renal cell carcinoma (RCC) in children is lacking. Occasional case report has been mentioned. Aims and objective of our study are to evaluate the clinical presentation and outcome in children with RCC. Patients and Methods: Records of 11 children and adolescence, from January 2007 to June 2011, who were treated for RCC were retrospectively analysed. Age, clinical presentation, any paraneoplastic symptom or sign, haematological, bio-chemical investigations, radiological imaging′s, operative details, pathological reports and treatment details were taken from hospital records and results were analysed. All patients were followed-up with complete haemogram, biochemical investigations, ultrasonography - whole abdomen and chest X-ray at 6 months interval and patients with stages 2 and 3 were also followed-up with contrast enhanced computed tomography - whole abdomen. They were followed-up for 2-5 years. Results: All had undergone open radical nephrectomy with eight hilar lymph node dissection and three formal lymphadenectomy. None had received adjuvant therapy. Four patients with stage 1 were well at 5, 4, 2.5 and 2 years. One patient with stage 1 was lost to follow-up. Three patients with stage 2 were well at 4, 3 and 2 years of follow-up while three with stage 3 were well at 5, 4 and 2 years of follow-up. Conclusions: Lymph node dissection not only improves the survival, but it guides one the exact pathological staging and one can adopt the more aggressive follow-up in advanced pathological staging and strict follow-up is mandatory. |
| first_indexed | 2024-12-20T05:44:33Z |
| format | Article |
| id | doaj.art-7f5e656cb050495492e96e3c567bd306 |
| institution | Directory Open Access Journal |
| issn | 0189-6725 0974-5998 |
| language | English |
| last_indexed | 2024-12-20T05:44:33Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | African Journal of Paediatric Surgery |
| spelling | doaj.art-7f5e656cb050495492e96e3c567bd3062022-12-21T19:51:22ZengWolters Kluwer Medknow PublicationsAfrican Journal of Paediatric Surgery0189-67250974-59982014-01-0111210110410.4103/0189-6725.132786Renal cell carcinoma in children and adolescence: Our experienceSuresh KumarPramod SharmaJittendra PratapPunit TiwariMalay K. BeraAnup K. KunduBackground: Literature on renal cell carcinoma (RCC) in children is lacking. Occasional case report has been mentioned. Aims and objective of our study are to evaluate the clinical presentation and outcome in children with RCC. Patients and Methods: Records of 11 children and adolescence, from January 2007 to June 2011, who were treated for RCC were retrospectively analysed. Age, clinical presentation, any paraneoplastic symptom or sign, haematological, bio-chemical investigations, radiological imaging′s, operative details, pathological reports and treatment details were taken from hospital records and results were analysed. All patients were followed-up with complete haemogram, biochemical investigations, ultrasonography - whole abdomen and chest X-ray at 6 months interval and patients with stages 2 and 3 were also followed-up with contrast enhanced computed tomography - whole abdomen. They were followed-up for 2-5 years. Results: All had undergone open radical nephrectomy with eight hilar lymph node dissection and three formal lymphadenectomy. None had received adjuvant therapy. Four patients with stage 1 were well at 5, 4, 2.5 and 2 years. One patient with stage 1 was lost to follow-up. Three patients with stage 2 were well at 4, 3 and 2 years of follow-up while three with stage 3 were well at 5, 4 and 2 years of follow-up. Conclusions: Lymph node dissection not only improves the survival, but it guides one the exact pathological staging and one can adopt the more aggressive follow-up in advanced pathological staging and strict follow-up is mandatory.http://www.afrjpaedsurg.org/article.asp?issn=0189-6725;year=2014;volume=11;issue=2;spage=101;epage=104;aulast=KumarChildhoodlymphadenectomyradical nephrectomyrenal cell carcinoma |
| spellingShingle | Suresh Kumar Pramod Sharma Jittendra Pratap Punit Tiwari Malay K. Bera Anup K. Kundu Renal cell carcinoma in children and adolescence: Our experience African Journal of Paediatric Surgery Childhood lymphadenectomy radical nephrectomy renal cell carcinoma |
| title | Renal cell carcinoma in children and adolescence: Our experience |
| title_full | Renal cell carcinoma in children and adolescence: Our experience |
| title_fullStr | Renal cell carcinoma in children and adolescence: Our experience |
| title_full_unstemmed | Renal cell carcinoma in children and adolescence: Our experience |
| title_short | Renal cell carcinoma in children and adolescence: Our experience |
| title_sort | renal cell carcinoma in children and adolescence our experience |
| topic | Childhood lymphadenectomy radical nephrectomy renal cell carcinoma |
| url | http://www.afrjpaedsurg.org/article.asp?issn=0189-6725;year=2014;volume=11;issue=2;spage=101;epage=104;aulast=Kumar |
| work_keys_str_mv | AT sureshkumar renalcellcarcinomainchildrenandadolescenceourexperience AT pramodsharma renalcellcarcinomainchildrenandadolescenceourexperience AT jittendrapratap renalcellcarcinomainchildrenandadolescenceourexperience AT punittiwari renalcellcarcinomainchildrenandadolescenceourexperience AT malaykbera renalcellcarcinomainchildrenandadolescenceourexperience AT anupkkundu renalcellcarcinomainchildrenandadolescenceourexperience |