MicroRNA-524 promotes cell proliferation by down-regulating PTEN expression in osteosarcoma

MicroRNA-524 promotes cell proliferation by down-regulating PTEN expression in osteosarcoma

Abstract Background Increasing numbers of studies have examined the correlation between specific miRNAs and tumours to enable their diagnosis and treatment. However, there are few reports regarding the concrete role and mechanism of miRNA in osteosarcoma. Methods The expression of miR-524 in osteosa...

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Bibliographic Details
Main Authors: Ming Zhuang, Xubin Qiu, Dong Cheng, Chenlei Zhu, Liang Chen
Format: Article
Language:English
Published: BMC 2018-08-01
Series:Cancer Cell International
Subjects:
MicroRNA-524
PTEN
Osteosarcoma
PI3K/AKT
Online Access:http://link.springer.com/article/10.1186/s12935-018-0612-1

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