Modifiable Pancreatic Ductal Adenocarcinoma (PDAC) Risk Factors
This study aims to summarize the modifiable risk factors for pancreatic ductal adenocarcinoma (PDAC) that have been known for a long time, as well as information from the most recent reports. As a cancer with a late diagnosis and poor prognosis, accurate analysis of PDAC risk factors is warranted. T...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-06-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/13/4318 |
| _version_ | 1797591421978411008 |
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| author | Natalia Michalak Ewa Małecka-Wojciesko |
| author_facet | Natalia Michalak Ewa Małecka-Wojciesko |
| author_sort | Natalia Michalak |
| collection | DOAJ |
| description | This study aims to summarize the modifiable risk factors for pancreatic ductal adenocarcinoma (PDAC) that have been known for a long time, as well as information from the most recent reports. As a cancer with a late diagnosis and poor prognosis, accurate analysis of PDAC risk factors is warranted. The incidence of this cancer continues to rise, and the five-year survival rate is the lowest with respect to other tumors. The influence of cigarette smoking, alcohol consumption, and chronic pancreatitis in increasing the risk of pancreatic ductal adenocarcinoma is continually being confirmed. There are also newly emerging reports relating to the impact of lifestyle, including physical activity, the gut and oral microbiome, and hepatotropic viruses. A precise understanding of PDAC risk factors can help to identify groups of high-risk patients, and this may contribute to population awareness and education as well as earlier diagnoses with possible better treatment outcomes. |
| first_indexed | 2024-03-11T01:37:11Z |
| format | Article |
| id | doaj.art-7f62ba70c3be48e19a35f75ec597faf9 |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T01:37:11Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-7f62ba70c3be48e19a35f75ec597faf92023-11-18T16:52:09ZengMDPI AGJournal of Clinical Medicine2077-03832023-06-011213431810.3390/jcm12134318Modifiable Pancreatic Ductal Adenocarcinoma (PDAC) Risk FactorsNatalia Michalak0Ewa Małecka-Wojciesko1Department of Digestive Tract Diseases, Medical University of Lodz, 90-419 Lodz, PolandDepartment of Digestive Tract Diseases, Medical University of Lodz, 90-419 Lodz, PolandThis study aims to summarize the modifiable risk factors for pancreatic ductal adenocarcinoma (PDAC) that have been known for a long time, as well as information from the most recent reports. As a cancer with a late diagnosis and poor prognosis, accurate analysis of PDAC risk factors is warranted. The incidence of this cancer continues to rise, and the five-year survival rate is the lowest with respect to other tumors. The influence of cigarette smoking, alcohol consumption, and chronic pancreatitis in increasing the risk of pancreatic ductal adenocarcinoma is continually being confirmed. There are also newly emerging reports relating to the impact of lifestyle, including physical activity, the gut and oral microbiome, and hepatotropic viruses. A precise understanding of PDAC risk factors can help to identify groups of high-risk patients, and this may contribute to population awareness and education as well as earlier diagnoses with possible better treatment outcomes.https://www.mdpi.com/2077-0383/12/13/4318pancreatic ductal adenocarcinomaPDACrisk factorspancreatic cancer |
| spellingShingle | Natalia Michalak Ewa Małecka-Wojciesko Modifiable Pancreatic Ductal Adenocarcinoma (PDAC) Risk Factors Journal of Clinical Medicine pancreatic ductal adenocarcinoma PDAC risk factors pancreatic cancer |
| title | Modifiable Pancreatic Ductal Adenocarcinoma (PDAC) Risk Factors |
| title_full | Modifiable Pancreatic Ductal Adenocarcinoma (PDAC) Risk Factors |
| title_fullStr | Modifiable Pancreatic Ductal Adenocarcinoma (PDAC) Risk Factors |
| title_full_unstemmed | Modifiable Pancreatic Ductal Adenocarcinoma (PDAC) Risk Factors |
| title_short | Modifiable Pancreatic Ductal Adenocarcinoma (PDAC) Risk Factors |
| title_sort | modifiable pancreatic ductal adenocarcinoma pdac risk factors |
| topic | pancreatic ductal adenocarcinoma PDAC risk factors pancreatic cancer |
| url | https://www.mdpi.com/2077-0383/12/13/4318 |
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