Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology
Since the embryonic stem cells have knocked the doorsteps, they have proved themselves in the field of science, research, and medicines, but the hovered restrictions confine their application in human welfare. Alternate approaches used to reprogram the cells to the pluripotent state were not up to p...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Veterinary World
2017-06-01
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| Series: | Veterinary World |
| Subjects: | |
| Online Access: | http://www.veterinaryworld.org/Vol.10/June-2017/12.pdf |
| _version_ | 1818648564332494848 |
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| author | N. Rawat M. K. Singh |
| author_facet | N. Rawat M. K. Singh |
| author_sort | N. Rawat |
| collection | DOAJ |
| description | Since the embryonic stem cells have knocked the doorsteps, they have proved themselves in the field of science, research, and medicines, but the hovered restrictions confine their application in human welfare. Alternate approaches used to reprogram the cells to the pluripotent state were not up to par, but the innovation of induced pluripotent stem cells (iPSCs) paved a new hope for the researchers. Soon after the discovery, iPSCs technology is undergoing renaissance day by day, i.e., from the use of genetic material to recombinant proteins and now only chemicals are employed to convert somatic cells to iPSCs. Thus, this technique is moving straightforward and productive at an astonishing pace. Here, we provide a brief introduction to iPSCs, the mechanism and methods for their generation, their prevailing and prospective applications and the future opportunities that can be expected from them. |
| first_indexed | 2024-12-17T01:20:26Z |
| format | Article |
| id | doaj.art-7f653e28f6344982bbdf0e7974f56269 |
| institution | Directory Open Access Journal |
| issn | 0972-8988 2231-0916 |
| language | English |
| last_indexed | 2024-12-17T01:20:26Z |
| publishDate | 2017-06-01 |
| publisher | Veterinary World |
| record_format | Article |
| series | Veterinary World |
| spelling | doaj.art-7f653e28f6344982bbdf0e7974f562692022-12-21T22:08:50ZengVeterinary WorldVeterinary World0972-89882231-09162017-06-0110664064910.14202/vetworld.2017.640-649Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biologyN. Rawat0M. K. Singh1Embryo Biotechnology Lab, Animal Biotechnology Centre, ICAR - National Dairy Research Institute, Karnal - 132 001, Haryana, India.Embryo Biotechnology Lab, Animal Biotechnology Centre, ICAR - National Dairy Research Institute, Karnal - 132 001, Haryana, India.Since the embryonic stem cells have knocked the doorsteps, they have proved themselves in the field of science, research, and medicines, but the hovered restrictions confine their application in human welfare. Alternate approaches used to reprogram the cells to the pluripotent state were not up to par, but the innovation of induced pluripotent stem cells (iPSCs) paved a new hope for the researchers. Soon after the discovery, iPSCs technology is undergoing renaissance day by day, i.e., from the use of genetic material to recombinant proteins and now only chemicals are employed to convert somatic cells to iPSCs. Thus, this technique is moving straightforward and productive at an astonishing pace. Here, we provide a brief introduction to iPSCs, the mechanism and methods for their generation, their prevailing and prospective applications and the future opportunities that can be expected from them.http://www.veterinaryworld.org/Vol.10/June-2017/12.pdfcellular reprogrammingembryonic stem cellsinduced pluripotent stem cellsstem cells |
| spellingShingle | N. Rawat M. K. Singh Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology Veterinary World cellular reprogramming embryonic stem cells induced pluripotent stem cells stem cells |
| title | Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology |
| title_full | Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology |
| title_fullStr | Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology |
| title_full_unstemmed | Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology |
| title_short | Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology |
| title_sort | induced pluripotent stem cell a headway in reprogramming with promising approach in regenerative biology |
| topic | cellular reprogramming embryonic stem cells induced pluripotent stem cells stem cells |
| url | http://www.veterinaryworld.org/Vol.10/June-2017/12.pdf |
| work_keys_str_mv | AT nrawat inducedpluripotentstemcellaheadwayinreprogrammingwithpromisingapproachinregenerativebiology AT mksingh inducedpluripotentstemcellaheadwayinreprogrammingwithpromisingapproachinregenerativebiology |