Dopaminergic mechanism underlying reward-encoding of punishment omission during reversal learning in Drosophila
Unexpected omission of aversive outcome is encoded as reward via activation of reward-encoding dopaminergic neurons in animals. The authors identify the Drosophila neural circuit through which reward-encoding dopaminergic neurons are activated when an olfactory cue is no longer paired with punishmen...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2021-02-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-021-21388-w |
| _version_ | 1818431137192607744 |
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| author | Li Yan McCurdy Preeti Sareen Pasha A. Davoudian Michael N. Nitabach |
| author_facet | Li Yan McCurdy Preeti Sareen Pasha A. Davoudian Michael N. Nitabach |
| author_sort | Li Yan McCurdy |
| collection | DOAJ |
| description | Unexpected omission of aversive outcome is encoded as reward via activation of reward-encoding dopaminergic neurons in animals. The authors identify the Drosophila neural circuit through which reward-encoding dopaminergic neurons are activated when an olfactory cue is no longer paired with punishment. |
| first_indexed | 2024-12-14T15:44:31Z |
| format | Article |
| id | doaj.art-7f6566e4a881478cb0affde699c2efeb |
| institution | Directory Open Access Journal |
| issn | 2041-1723 |
| language | English |
| last_indexed | 2024-12-14T15:44:31Z |
| publishDate | 2021-02-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Nature Communications |
| spelling | doaj.art-7f6566e4a881478cb0affde699c2efeb2022-12-21T22:55:32ZengNature PortfolioNature Communications2041-17232021-02-0112111710.1038/s41467-021-21388-wDopaminergic mechanism underlying reward-encoding of punishment omission during reversal learning in DrosophilaLi Yan McCurdy0Preeti Sareen1Pasha A. Davoudian2Michael N. Nitabach3Interdepartmental Neuroscience Program, Yale UniversityDepartment of Cellular & Molecular Physiology, Yale UniversityDepartment of Neuroscience, Yale UniversityDepartment of Cellular & Molecular Physiology, Yale UniversityUnexpected omission of aversive outcome is encoded as reward via activation of reward-encoding dopaminergic neurons in animals. The authors identify the Drosophila neural circuit through which reward-encoding dopaminergic neurons are activated when an olfactory cue is no longer paired with punishment.https://doi.org/10.1038/s41467-021-21388-w |
| spellingShingle | Li Yan McCurdy Preeti Sareen Pasha A. Davoudian Michael N. Nitabach Dopaminergic mechanism underlying reward-encoding of punishment omission during reversal learning in Drosophila Nature Communications |
| title | Dopaminergic mechanism underlying reward-encoding of punishment omission during reversal learning in Drosophila |
| title_full | Dopaminergic mechanism underlying reward-encoding of punishment omission during reversal learning in Drosophila |
| title_fullStr | Dopaminergic mechanism underlying reward-encoding of punishment omission during reversal learning in Drosophila |
| title_full_unstemmed | Dopaminergic mechanism underlying reward-encoding of punishment omission during reversal learning in Drosophila |
| title_short | Dopaminergic mechanism underlying reward-encoding of punishment omission during reversal learning in Drosophila |
| title_sort | dopaminergic mechanism underlying reward encoding of punishment omission during reversal learning in drosophila |
| url | https://doi.org/10.1038/s41467-021-21388-w |
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