T Follicular Helper Cells As a New Target for Immunosuppressive Therapies

T Follicular Helper Cells As a New Target for Immunosuppressive Therapies

Over the past decade, antibody-mediated (humoral) rejection has been recognized as a common cause of graft dysfunction after organ transplantation and an important determinant for graft loss. In humoral alloimmunity, T follicular helper (Tfh) cells play a crucial role, because they help naïve B cell...

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Bibliographic Details
Main Authors:	Lin Yan, Kitty de Leur, Rudi W. Hendriks, Luc J. W. van der Laan, Yunying Shi, Lanlan Wang, Carla C. Baan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2017-11-01
Series:	Frontiers in Immunology
Subjects:	T follicular helper cells immunosuppression humoral immunity transplantation allograft rejection donor-specific antibodies
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01510/full

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