Sleep restriction suppresses the activity of the hypothalamo-pituitary-adrenal axis but does not affect the autonomic nervous system
Sleep restriction is likely to affect the activities of stress axes, namely the hypothalamic-pituitary-adrenal axis (HPA) and the autonomic nervous system (ANS). Sleep restriction is likely to be experienced by everybody, yet the number of studies on that subject is very scarce. The current study ai...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Society of Turaz Bilim
2022-06-01
|
| Series: | Medicine Science |
| Subjects: | |
| Online Access: | http://www.ejmanager.com/fulltextpdf.php?mno=137044 |
| _version_ | 1797327895654301696 |
|---|---|
| author | Cihat Ucar Tuba Ozgocer Sedat Yildiz |
| author_facet | Cihat Ucar Tuba Ozgocer Sedat Yildiz |
| author_sort | Cihat Ucar |
| collection | DOAJ |
| description | Sleep restriction is likely to affect the activities of stress axes, namely the hypothalamic-pituitary-adrenal axis (HPA) and the autonomic nervous system (ANS). Sleep restriction is likely to be experienced by everybody, yet the number of studies on that subject is very scarce. The current study aimed to examine the effects of sleep restriction on cortisol awakening response (CAR) as an indicator of HPA and heart rate variability (HRV) as an indicator of ANS activity. Participants (second-year medical students) were divided into two groups as sleep restricting group (n=27, sleeping at 02:00 p.m., waking up at 06:30 a.m.) and normal sleep duration group (n=25, sleeping at 11:00 p.m., waking up at 06:30 a.m.). The participants who filled in sleep dairies provided salivary samples (taken at 0, 15, 30, and 60 min post-awakening) for measurement of CAR and had an electrocardiogram recording (for 5 min) for determination of HRV. Mann-Whitney U test was used for statistical analyses. Sleep restriction reduced cortisol concentrations 15 and 30 minutes following awakening (p0.05). Sleep diaries showed that awakening problem scores were higher but daily disturbed sleep score was lower in the restricted sleep group (p [Med-Science 2022; 11(2.000): 682-9] |
| first_indexed | 2024-03-08T06:43:24Z |
| format | Article |
| id | doaj.art-7f6e33c5059c4188a238c05b863d5f46 |
| institution | Directory Open Access Journal |
| issn | 2147-0634 |
| language | English |
| last_indexed | 2024-03-08T06:43:24Z |
| publishDate | 2022-06-01 |
| publisher | Society of Turaz Bilim |
| record_format | Article |
| series | Medicine Science |
| spelling | doaj.art-7f6e33c5059c4188a238c05b863d5f462024-02-03T08:19:14ZengSociety of Turaz BilimMedicine Science2147-06342022-06-01112682910.5455/medscience.2021.11.363137044Sleep restriction suppresses the activity of the hypothalamo-pituitary-adrenal axis but does not affect the autonomic nervous systemCihat Ucar0Tuba Ozgocer1Sedat Yildiz2Adiyaman University Faculty of Medicine, Department of Physiology Harran University, Faculty of Medicine, Department of Physiology Inonu University, Faculty of Medicine, Department of PhysiologySleep restriction is likely to affect the activities of stress axes, namely the hypothalamic-pituitary-adrenal axis (HPA) and the autonomic nervous system (ANS). Sleep restriction is likely to be experienced by everybody, yet the number of studies on that subject is very scarce. The current study aimed to examine the effects of sleep restriction on cortisol awakening response (CAR) as an indicator of HPA and heart rate variability (HRV) as an indicator of ANS activity. Participants (second-year medical students) were divided into two groups as sleep restricting group (n=27, sleeping at 02:00 p.m., waking up at 06:30 a.m.) and normal sleep duration group (n=25, sleeping at 11:00 p.m., waking up at 06:30 a.m.). The participants who filled in sleep dairies provided salivary samples (taken at 0, 15, 30, and 60 min post-awakening) for measurement of CAR and had an electrocardiogram recording (for 5 min) for determination of HRV. Mann-Whitney U test was used for statistical analyses. Sleep restriction reduced cortisol concentrations 15 and 30 minutes following awakening (p0.05). Sleep diaries showed that awakening problem scores were higher but daily disturbed sleep score was lower in the restricted sleep group (p [Med-Science 2022; 11(2.000): 682-9]http://www.ejmanager.com/fulltextpdf.php?mno=137044sleephpa axiscortisol awakening responsesalivary cortisol |
| spellingShingle | Cihat Ucar Tuba Ozgocer Sedat Yildiz Sleep restriction suppresses the activity of the hypothalamo-pituitary-adrenal axis but does not affect the autonomic nervous system Medicine Science sleep hpa axis cortisol awakening response salivary cortisol |
| title | Sleep restriction suppresses the activity of the hypothalamo-pituitary-adrenal axis but does not affect the autonomic nervous system |
| title_full | Sleep restriction suppresses the activity of the hypothalamo-pituitary-adrenal axis but does not affect the autonomic nervous system |
| title_fullStr | Sleep restriction suppresses the activity of the hypothalamo-pituitary-adrenal axis but does not affect the autonomic nervous system |
| title_full_unstemmed | Sleep restriction suppresses the activity of the hypothalamo-pituitary-adrenal axis but does not affect the autonomic nervous system |
| title_short | Sleep restriction suppresses the activity of the hypothalamo-pituitary-adrenal axis but does not affect the autonomic nervous system |
| title_sort | sleep restriction suppresses the activity of the hypothalamo pituitary adrenal axis but does not affect the autonomic nervous system |
| topic | sleep hpa axis cortisol awakening response salivary cortisol |
| url | http://www.ejmanager.com/fulltextpdf.php?mno=137044 |
| work_keys_str_mv | AT cihatucar sleeprestrictionsuppressestheactivityofthehypothalamopituitaryadrenalaxisbutdoesnotaffecttheautonomicnervoussystem AT tubaozgocer sleeprestrictionsuppressestheactivityofthehypothalamopituitaryadrenalaxisbutdoesnotaffecttheautonomicnervoussystem AT sedatyildiz sleeprestrictionsuppressestheactivityofthehypothalamopituitaryadrenalaxisbutdoesnotaffecttheautonomicnervoussystem |