Unsuspected Prostate Cancer After Cystoprostatectomy: A Comparison Between Two Periods in Taiwan

The incidence of and mortality rate from prostate cancer have been rising rapidly in Taiwan in recent years. Prostate specimens obtained during cystoprostatectomy may play a role in the study of prostate cancer evolution. Methods: From January 2001 to December 2005, we collected and examined retrosp...

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Bibliographic Details
Main Authors: Jian-Ri Li, Chi-Rei Yang, John Wang, Yen-Chuan Ou, Hao-Chung Ho, Chen-Li Cheng
Format: Article
Language:English
Published: Elsevier 2009-05-01
Series:Journal of the Formosan Medical Association
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Online Access:http://www.sciencedirect.com/science/article/pii/S0929664609600851
Description
Summary:The incidence of and mortality rate from prostate cancer have been rising rapidly in Taiwan in recent years. Prostate specimens obtained during cystoprostatectomy may play a role in the study of prostate cancer evolution. Methods: From January 2001 to December 2005, we collected and examined retrospectively 65 prostate specimens obtained from patients during cystoprostatectomy performed for various conditions. Fourteen patients (21%) had evidence of prostate cancer and 11 (17%) had high-grade prostatic intraepithelial neoplasia. Results: We compared our results with those of a previous study conducted at the same institute from 1992 to 1997. There was no statistical difference between the two groups in unsuspected prostate cancer prevalence (p = 0.263), but the prevalence declined from 32.7% to 21.5%. Conclusion: The results imply that the epidemiological decline in unsuspected prostate cancer in central Taiwan may be associated with the wide application of testing for prostatic specific antigen.
ISSN:0929-6646