Upregulation of hepatic LDL transport by n-3 fatty acids in LDL receptor knockout mice

Upregulation of hepatic LDL transport by n-3 fatty acids in LDL receptor knockout mice

We determined the effects of dietary n-6 and n-3 polyunsaturated fatty acids (PUFA) on parameters of plasma lipoprotein and hepatic lipid metabolism in LDL receptor (LDLr) knockout mice. Dietary n-3 PUFA decreased the rate of appearance and increased the hepatic clearance of IDL/LDL resulting in a m...

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Bibliographic Details
Main Authors: Chandna Vasandani, Abdallah I. Kafrouni, Antonella Caronna, Yuriy Bashmakov, Michael Gotthardt, Jay D. Horton, David K. Spady
Format: Article
Language:English
Published: Elsevier 2002-05-01
Series:Journal of Lipid Research
Subjects:
polyunsaturated fatty acids
fish oil
liver
lipoproteins
cholesterol
triglyceride
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520301206

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