The Role of the Thioredoxin System in Brain Diseases

The thioredoxin system, consisting of thioredoxin (Trx), thioredoxin reductase (TrxR), and NADPH, plays a fundamental role in the control of antioxidant defenses, cell proliferation, redox states, and apoptosis. Aberrations in the Trx system may lead to increased oxidative stress toxicity and neurod...

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Bibliographic Details
Main Authors: Geir Bjørklund, Lili Zou, Massimiliano Peana, Christos T. Chasapis, Tony Hangan, Jun Lu, Michael Maes
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Antioxidants
Subjects:
Online Access:https://www.mdpi.com/2076-3921/11/11/2161

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