The Role of the Thioredoxin System in Brain Diseases
The thioredoxin system, consisting of thioredoxin (Trx), thioredoxin reductase (TrxR), and NADPH, plays a fundamental role in the control of antioxidant defenses, cell proliferation, redox states, and apoptosis. Aberrations in the Trx system may lead to increased oxidative stress toxicity and neurod...
Main Authors: | Geir Bjørklund, Lili Zou, Massimiliano Peana, Christos T. Chasapis, Tony Hangan, Jun Lu, Michael Maes |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-10-01
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Series: | Antioxidants |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-3921/11/11/2161 |
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