Exercise and microbiome: From big data to therapy
Exercise is a vital component in maintaining optimal health and serves as a prospective therapeutic intervention for various diseases. The human microbiome, comprised of trillions of microorganisms, plays a crucial role in overall health. Given the advancements in microbiome research, substantial da...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-01-01
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| Series: | Computational and Structural Biotechnology Journal |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037023003902 |
| _version_ | 1827577609200861184 |
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| author | Danni Meng Songwei Ai Michail Spanos Xiaohui Shi Guoping Li Dragos Cretoiu Qiulian Zhou Junjie Xiao |
| author_facet | Danni Meng Songwei Ai Michail Spanos Xiaohui Shi Guoping Li Dragos Cretoiu Qiulian Zhou Junjie Xiao |
| author_sort | Danni Meng |
| collection | DOAJ |
| description | Exercise is a vital component in maintaining optimal health and serves as a prospective therapeutic intervention for various diseases. The human microbiome, comprised of trillions of microorganisms, plays a crucial role in overall health. Given the advancements in microbiome research, substantial databases have been created to decipher the functionality and mechanisms of the microbiome in health and disease contexts. This review presents an initial overview of microbiomics development and related databases, followed by an in-depth description of the multi-omics technologies for microbiome. It subsequently synthesizes the research pertaining to exercise-induced modifications of the microbiome and diseases that impact the microbiome. Finally, it highlights the potential therapeutic implications of an exercise-modulated microbiome in intestinal disease, obesity and diabetes, cardiovascular disease, and immune/inflammation-related diseases. |
| first_indexed | 2024-03-08T21:30:12Z |
| format | Article |
| id | doaj.art-7f74e1e15ea14598a3f0fc3b81448c5f |
| institution | Directory Open Access Journal |
| issn | 2001-0370 |
| language | English |
| last_indexed | 2024-03-08T21:30:12Z |
| publishDate | 2023-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Computational and Structural Biotechnology Journal |
| spelling | doaj.art-7f74e1e15ea14598a3f0fc3b81448c5f2023-12-21T07:32:22ZengElsevierComputational and Structural Biotechnology Journal2001-03702023-01-012154345445Exercise and microbiome: From big data to therapyDanni Meng0Songwei Ai1Michail Spanos2Xiaohui Shi3Guoping Li4Dragos Cretoiu5Qiulian Zhou6Junjie Xiao7Institute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People’s Hospital of Nantong), School of Medicine, Shanghai University, Nantong 226011, China; Cardiac Regeneration and Ageing Lab, Institute of Cardiovascular Sciences, Shanghai Engineering Research Center of Organ Repair, School of Life Science, Shanghai University, Shanghai 200444, ChinaInstitute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People’s Hospital of Nantong), School of Medicine, Shanghai University, Nantong 226011, China; Cardiac Regeneration and Ageing Lab, Institute of Cardiovascular Sciences, Shanghai Engineering Research Center of Organ Repair, School of Life Science, Shanghai University, Shanghai 200444, ChinaCardiovascular Division of the Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USAInstitute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People’s Hospital of Nantong), School of Medicine, Shanghai University, Nantong 226011, China; Cardiac Regeneration and Ageing Lab, Institute of Cardiovascular Sciences, Shanghai Engineering Research Center of Organ Repair, School of Life Science, Shanghai University, Shanghai 200444, ChinaCardiovascular Division of the Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USADepartment of Medical Genetics, Carol Davila University of Medicine and Pharmacy, Bucharest 020031, Romania; Materno-Fetal Assistance Excellence Unit, Alessandrescu-Rusescu National Institute for Mother and Child Health, Bucharest 011062, RomaniaInstitute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People’s Hospital of Nantong), School of Medicine, Shanghai University, Nantong 226011, China; Cardiac Regeneration and Ageing Lab, Institute of Cardiovascular Sciences, Shanghai Engineering Research Center of Organ Repair, School of Life Science, Shanghai University, Shanghai 200444, China; Corresponding authors at: Institute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People’s Hospital of Nantong), School of Medicine, Shanghai University, Nantong 226011, China.Institute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People’s Hospital of Nantong), School of Medicine, Shanghai University, Nantong 226011, China; Cardiac Regeneration and Ageing Lab, Institute of Cardiovascular Sciences, Shanghai Engineering Research Center of Organ Repair, School of Life Science, Shanghai University, Shanghai 200444, China; Corresponding authors at: Institute of Geriatrics (Shanghai University), Affiliated Nantong Hospital of Shanghai University (The Sixth People’s Hospital of Nantong), School of Medicine, Shanghai University, Nantong 226011, China.Exercise is a vital component in maintaining optimal health and serves as a prospective therapeutic intervention for various diseases. The human microbiome, comprised of trillions of microorganisms, plays a crucial role in overall health. Given the advancements in microbiome research, substantial databases have been created to decipher the functionality and mechanisms of the microbiome in health and disease contexts. This review presents an initial overview of microbiomics development and related databases, followed by an in-depth description of the multi-omics technologies for microbiome. It subsequently synthesizes the research pertaining to exercise-induced modifications of the microbiome and diseases that impact the microbiome. Finally, it highlights the potential therapeutic implications of an exercise-modulated microbiome in intestinal disease, obesity and diabetes, cardiovascular disease, and immune/inflammation-related diseases.http://www.sciencedirect.com/science/article/pii/S2001037023003902Physical exerciseMicrobiomeMicrobiomicsTherapy |
| spellingShingle | Danni Meng Songwei Ai Michail Spanos Xiaohui Shi Guoping Li Dragos Cretoiu Qiulian Zhou Junjie Xiao Exercise and microbiome: From big data to therapy Computational and Structural Biotechnology Journal Physical exercise Microbiome Microbiomics Therapy |
| title | Exercise and microbiome: From big data to therapy |
| title_full | Exercise and microbiome: From big data to therapy |
| title_fullStr | Exercise and microbiome: From big data to therapy |
| title_full_unstemmed | Exercise and microbiome: From big data to therapy |
| title_short | Exercise and microbiome: From big data to therapy |
| title_sort | exercise and microbiome from big data to therapy |
| topic | Physical exercise Microbiome Microbiomics Therapy |
| url | http://www.sciencedirect.com/science/article/pii/S2001037023003902 |
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