A pilot study of cognitive behavioural therapy integrated with activity pacing for fatigued breast cancer patients undergoing chemotherapy in Ethiopia
BackgroundFatigue is a common symptom in breast cancer patients, and it is one of the major factors that influence the quality of life (QoL). Cognitive behavioural therapy (CBT) has been recommended to manage cancer-related fatigue. In this study, CBT will be integrated with activity pacing (AP), wh...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-09-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2022.847400/full |
| _version_ | 1811272324957077504 |
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| author | Mikiyas Amare Getu Mikiyas Amare Getu Mikiyas Amare Getu Changying Chen Changying Chen Adamu Addissie Adamu Addissie Edom Seife Panpan Wang Eva Johanna Kantelhardt Eva Johanna Kantelhardt |
| author_facet | Mikiyas Amare Getu Mikiyas Amare Getu Mikiyas Amare Getu Changying Chen Changying Chen Adamu Addissie Adamu Addissie Edom Seife Panpan Wang Eva Johanna Kantelhardt Eva Johanna Kantelhardt |
| author_sort | Mikiyas Amare Getu |
| collection | DOAJ |
| description | BackgroundFatigue is a common symptom in breast cancer patients, and it is one of the major factors that influence the quality of life (QoL). Cognitive behavioural therapy (CBT) has been recommended to manage cancer-related fatigue. In this study, CBT will be integrated with activity pacing (AP), which can help breast cancer patients achieve a balance between activity and rest. Therefore, this pilot study aimed to investigate the acceptability, feasibility, and efficacy of the CBT-AP intervention.MethodsA total of 10 fatigued breast cancer patients undergoing chemotherapy were included in the study. The acceptability and feasibility of the study were measured by the patient recruitment rate, attrition rate, intervention fidelity, intervention compliance, and therapist’s and participant’s evaluations of the intervention. The outcomes were measured at baseline and at 6 weeks of intervention.ResultsThe pre–post study suggested that CBT-AP was found to be acceptable and feasible for fatigued breast cancer patients undergoing chemotherapy. Among 27 eligible participants, 10 (37.03%) participants accepted our invitation to participate in the study. One participant dropped out from the intervention because of serious illness, and the dropout rate was 10%.Both the intervention fidelity and intervention compliance were found to be satisfactory.Fatigue severity [Brief Fatigue Inventory (BFI)] was reduced in 77.77% of participants from baseline to 6 weeks of intervention. The global health status/QoL scale and physical, emotional, and social functioning scales were improved from baseline to 6 weeks of intervention. All symptom scales, except constipation, diarrhea, and financial difficulties, were decreased after the intervention. Depression [Public Health Questionnaire (PHQ)-9] was reduced in 55.55% of participants.ConclusionThis study suggested that CBT-AP is an acceptable, feasible, and potentially efficacious intervention to reduce fatigue and improve the QoL of breast cancer patients. The efficacy of a CBT-AP programme is going to be investigated in subsequent larger randomized clinical trials. |
| first_indexed | 2024-04-12T22:38:12Z |
| format | Article |
| id | doaj.art-7f78a28cf6e640f8b79ad1278dbc31e7 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-04-12T22:38:12Z |
| publishDate | 2022-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-7f78a28cf6e640f8b79ad1278dbc31e72022-12-22T03:13:48ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2022-09-011210.3389/fonc.2022.847400847400A pilot study of cognitive behavioural therapy integrated with activity pacing for fatigued breast cancer patients undergoing chemotherapy in EthiopiaMikiyas Amare Getu0Mikiyas Amare Getu1Mikiyas Amare Getu2Changying Chen3Changying Chen4Adamu Addissie5Adamu Addissie6Edom Seife7Panpan Wang8Eva Johanna Kantelhardt9Eva Johanna Kantelhardt10Department of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Clinical Nursing, School of Nursing and Health, Zhengzhou University, Zhengzhou, ChinaGlobal Health Working Group, Martin-Luther-University, Halle (Saale), GermanyDepartment of Oncology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Clinical Nursing, School of Nursing and Health, Zhengzhou University, Zhengzhou, ChinaInstitute of Medical Epidemiology, Biostatistics and Informatics, Martin-Luther-University, Halle (Saale), GermanySchool of Public Health, Department of Preventive Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, EthiopiaTikur Anbessa Specialized Hospital, Department of Oncology, College of Health Science, Addis Ababa University, Addis Ababa, EthiopiaDepartment of Community Health Nursing, School of Nursing and Health, Zhengzhou University, Halle (Saale), GermanyInstitute of Medical Epidemiology, Biostatistics and Informatics, Martin-Luther-University, Halle (Saale), GermanyDepartment of Gynecology, Martin-Luther-University, Halle (Saale), GermanyBackgroundFatigue is a common symptom in breast cancer patients, and it is one of the major factors that influence the quality of life (QoL). Cognitive behavioural therapy (CBT) has been recommended to manage cancer-related fatigue. In this study, CBT will be integrated with activity pacing (AP), which can help breast cancer patients achieve a balance between activity and rest. Therefore, this pilot study aimed to investigate the acceptability, feasibility, and efficacy of the CBT-AP intervention.MethodsA total of 10 fatigued breast cancer patients undergoing chemotherapy were included in the study. The acceptability and feasibility of the study were measured by the patient recruitment rate, attrition rate, intervention fidelity, intervention compliance, and therapist’s and participant’s evaluations of the intervention. The outcomes were measured at baseline and at 6 weeks of intervention.ResultsThe pre–post study suggested that CBT-AP was found to be acceptable and feasible for fatigued breast cancer patients undergoing chemotherapy. Among 27 eligible participants, 10 (37.03%) participants accepted our invitation to participate in the study. One participant dropped out from the intervention because of serious illness, and the dropout rate was 10%.Both the intervention fidelity and intervention compliance were found to be satisfactory.Fatigue severity [Brief Fatigue Inventory (BFI)] was reduced in 77.77% of participants from baseline to 6 weeks of intervention. The global health status/QoL scale and physical, emotional, and social functioning scales were improved from baseline to 6 weeks of intervention. All symptom scales, except constipation, diarrhea, and financial difficulties, were decreased after the intervention. Depression [Public Health Questionnaire (PHQ)-9] was reduced in 55.55% of participants.ConclusionThis study suggested that CBT-AP is an acceptable, feasible, and potentially efficacious intervention to reduce fatigue and improve the QoL of breast cancer patients. The efficacy of a CBT-AP programme is going to be investigated in subsequent larger randomized clinical trials.https://www.frontiersin.org/articles/10.3389/fonc.2022.847400/fullbreast cancercognitive behavioural therapyfatiguequality of lifedepressionpilot study |
| spellingShingle | Mikiyas Amare Getu Mikiyas Amare Getu Mikiyas Amare Getu Changying Chen Changying Chen Adamu Addissie Adamu Addissie Edom Seife Panpan Wang Eva Johanna Kantelhardt Eva Johanna Kantelhardt A pilot study of cognitive behavioural therapy integrated with activity pacing for fatigued breast cancer patients undergoing chemotherapy in Ethiopia Frontiers in Oncology breast cancer cognitive behavioural therapy fatigue quality of life depression pilot study |
| title | A pilot study of cognitive behavioural therapy integrated with activity pacing for fatigued breast cancer patients undergoing chemotherapy in Ethiopia |
| title_full | A pilot study of cognitive behavioural therapy integrated with activity pacing for fatigued breast cancer patients undergoing chemotherapy in Ethiopia |
| title_fullStr | A pilot study of cognitive behavioural therapy integrated with activity pacing for fatigued breast cancer patients undergoing chemotherapy in Ethiopia |
| title_full_unstemmed | A pilot study of cognitive behavioural therapy integrated with activity pacing for fatigued breast cancer patients undergoing chemotherapy in Ethiopia |
| title_short | A pilot study of cognitive behavioural therapy integrated with activity pacing for fatigued breast cancer patients undergoing chemotherapy in Ethiopia |
| title_sort | pilot study of cognitive behavioural therapy integrated with activity pacing for fatigued breast cancer patients undergoing chemotherapy in ethiopia |
| topic | breast cancer cognitive behavioural therapy fatigue quality of life depression pilot study |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2022.847400/full |
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