Biosynthesis of spinel nickel ferrite nanowhiskers and their biomedical applications
Abstract Greener methods for the synthesis of various nanostructures with well-organized characteristics and biomedical applicability have demonstrated several advantages, including simplicity, low toxicity, cost-effectiveness, and eco-friendliness. Spinel nickel ferrite (NiFe2O4) nanowhiskers with...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2021-08-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-021-96918-z |
| _version_ | 1818683768258428928 |
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| author | Hajar Q. Alijani Siavash Iravani Shahram Pourseyedi Masoud Torkzadeh-Mahani Mahmood Barani Mehrdad Khatami |
| author_facet | Hajar Q. Alijani Siavash Iravani Shahram Pourseyedi Masoud Torkzadeh-Mahani Mahmood Barani Mehrdad Khatami |
| author_sort | Hajar Q. Alijani |
| collection | DOAJ |
| description | Abstract Greener methods for the synthesis of various nanostructures with well-organized characteristics and biomedical applicability have demonstrated several advantages, including simplicity, low toxicity, cost-effectiveness, and eco-friendliness. Spinel nickel ferrite (NiFe2O4) nanowhiskers with rod-like structures were synthesized using a simple and green method; these nanostructures were evaluated by X-ray diffraction analysis, transmission electron microscopy, scanning electron microscopy, and X-ray energy diffraction spectroscopy. Additionally, the prepared nanowhiskers could significantly reduce the survival of Leishmania major promastigotes, at a concentration of 500 μg/mL; the survival of promastigotes was reduced to ≃ 26%. According to the results obtained from MTT test (in vitro), it can be proposed that further studies should be conducted to evaluate anti-leishmaniasis activity of these types of nanowhiskers in animal models. |
| first_indexed | 2024-12-17T10:39:59Z |
| format | Article |
| id | doaj.art-7f78aa274f404eaaa531d5495192a0ab |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-12-17T10:39:59Z |
| publishDate | 2021-08-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-7f78aa274f404eaaa531d5495192a0ab2022-12-21T21:52:17ZengNature PortfolioScientific Reports2045-23222021-08-011111710.1038/s41598-021-96918-zBiosynthesis of spinel nickel ferrite nanowhiskers and their biomedical applicationsHajar Q. Alijani0Siavash Iravani1Shahram Pourseyedi2Masoud Torkzadeh-Mahani3Mahmood Barani4Mehrdad Khatami5Department of Biotechnology, Shahid Bahonar University of KermanFaculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical SciencesDepartment of Biotechnology, Shahid Bahonar University of KermanBiotechnology Department, Institute of Science and High Technology and Environmental Sciences, Graduate University of Advanced TechnologyMedical Mycology and Bacteriology Research Center, Kerman University of Medical SciencesNoncommunicable Diseases Research Center, Bam University of Medical SciencesAbstract Greener methods for the synthesis of various nanostructures with well-organized characteristics and biomedical applicability have demonstrated several advantages, including simplicity, low toxicity, cost-effectiveness, and eco-friendliness. Spinel nickel ferrite (NiFe2O4) nanowhiskers with rod-like structures were synthesized using a simple and green method; these nanostructures were evaluated by X-ray diffraction analysis, transmission electron microscopy, scanning electron microscopy, and X-ray energy diffraction spectroscopy. Additionally, the prepared nanowhiskers could significantly reduce the survival of Leishmania major promastigotes, at a concentration of 500 μg/mL; the survival of promastigotes was reduced to ≃ 26%. According to the results obtained from MTT test (in vitro), it can be proposed that further studies should be conducted to evaluate anti-leishmaniasis activity of these types of nanowhiskers in animal models.https://doi.org/10.1038/s41598-021-96918-z |
| spellingShingle | Hajar Q. Alijani Siavash Iravani Shahram Pourseyedi Masoud Torkzadeh-Mahani Mahmood Barani Mehrdad Khatami Biosynthesis of spinel nickel ferrite nanowhiskers and their biomedical applications Scientific Reports |
| title | Biosynthesis of spinel nickel ferrite nanowhiskers and their biomedical applications |
| title_full | Biosynthesis of spinel nickel ferrite nanowhiskers and their biomedical applications |
| title_fullStr | Biosynthesis of spinel nickel ferrite nanowhiskers and their biomedical applications |
| title_full_unstemmed | Biosynthesis of spinel nickel ferrite nanowhiskers and their biomedical applications |
| title_short | Biosynthesis of spinel nickel ferrite nanowhiskers and their biomedical applications |
| title_sort | biosynthesis of spinel nickel ferrite nanowhiskers and their biomedical applications |
| url | https://doi.org/10.1038/s41598-021-96918-z |
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