A case of treatment-induced neuropathy in an adolescent with type 1 diabetes
Treatment-induced neuropathy (TIN) in diabetes is an acute and painful yet completely reversible small fiber neuropathy precipitated by a rapid improvement in glycemic control. TIN is rare in children. A 16-year-old girl developed symmetrical painful neuropathy of the foot, autonomic neuropathy, and...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Korean Society of Pediatric Endocrinology
2019-09-01
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| Series: | Annals of Pediatric Endocrinology & Metabolism |
| Subjects: | |
| Online Access: | http://e-apem.org/upload/pdf/apem-2019-24-3-203.pdf |
| _version_ | 1818299391667077120 |
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| author | Niranjana Varadharaju Dhivyalakshmi Jeevarathnam Mahalakshmi Rajan Vinoth Ponnurangam Nagarajan Saji James |
| author_facet | Niranjana Varadharaju Dhivyalakshmi Jeevarathnam Mahalakshmi Rajan Vinoth Ponnurangam Nagarajan Saji James |
| author_sort | Niranjana Varadharaju |
| collection | DOAJ |
| description | Treatment-induced neuropathy (TIN) in diabetes is an acute and painful yet completely reversible small fiber neuropathy precipitated by a rapid improvement in glycemic control. TIN is rare in children. A 16-year-old girl developed symmetrical painful neuropathy of the foot, autonomic neuropathy, and retinopathy 5 weeks after the diagnosis of type 1 diabetes. All causative workups were negative except for a drop-in hemoglobin A1c (HbA1c) from 17.4% to 7%, which fit with a diagnosis of TIN. Following symptomatic management, her neuropathy and retinopathy completely resolved in 2 months. Currently, she is 18 years old and doing well (HbA1c, 7.4%) without any recurrence of TIN. TIN should be suspected in any child presenting with recent-onset type 1 diabetes and acute onset neuropathy. Our case represents an unreported scenario of the rapid progression in TIN. Awareness among clinicians about this rare but completely reversible condition is necessary to ensure proper management and adherence to glycemic control. |
| first_indexed | 2024-12-13T04:50:29Z |
| format | Article |
| id | doaj.art-7f7a452e4a0840ee855be806c8c08ea3 |
| institution | Directory Open Access Journal |
| issn | 2287-1012 2287-1292 |
| language | English |
| last_indexed | 2024-12-13T04:50:29Z |
| publishDate | 2019-09-01 |
| publisher | Korean Society of Pediatric Endocrinology |
| record_format | Article |
| series | Annals of Pediatric Endocrinology & Metabolism |
| spelling | doaj.art-7f7a452e4a0840ee855be806c8c08ea32022-12-21T23:59:02ZengKorean Society of Pediatric EndocrinologyAnnals of Pediatric Endocrinology & Metabolism2287-10122287-12922019-09-0124320320610.6065/apem.2019.24.3.203783A case of treatment-induced neuropathy in an adolescent with type 1 diabetesNiranjana Varadharaju0Dhivyalakshmi Jeevarathnam1Mahalakshmi Rajan2Vinoth Ponnurangam Nagarajan3Saji James4 Sri Ramachandra Medical College, Chennai, India Division of Paediatric Endocrinology, Department of Pediatrics, Sri Ramachandra Medical College, Chennai, India Department of Pediatrics, Sri Ramachandra Medical College, Chennai, India Department of Pediatrics, Sri Ramachandra Medical College, Chennai, India Department of Pediatrics, Sri Ramachandra Medical College, Chennai, IndiaTreatment-induced neuropathy (TIN) in diabetes is an acute and painful yet completely reversible small fiber neuropathy precipitated by a rapid improvement in glycemic control. TIN is rare in children. A 16-year-old girl developed symmetrical painful neuropathy of the foot, autonomic neuropathy, and retinopathy 5 weeks after the diagnosis of type 1 diabetes. All causative workups were negative except for a drop-in hemoglobin A1c (HbA1c) from 17.4% to 7%, which fit with a diagnosis of TIN. Following symptomatic management, her neuropathy and retinopathy completely resolved in 2 months. Currently, she is 18 years old and doing well (HbA1c, 7.4%) without any recurrence of TIN. TIN should be suspected in any child presenting with recent-onset type 1 diabetes and acute onset neuropathy. Our case represents an unreported scenario of the rapid progression in TIN. Awareness among clinicians about this rare but completely reversible condition is necessary to ensure proper management and adherence to glycemic control.http://e-apem.org/upload/pdf/apem-2019-24-3-203.pdfPainful neuropathyAutonomic neuropathyType 1 diabetes mellitusChildGlycemic control |
| spellingShingle | Niranjana Varadharaju Dhivyalakshmi Jeevarathnam Mahalakshmi Rajan Vinoth Ponnurangam Nagarajan Saji James A case of treatment-induced neuropathy in an adolescent with type 1 diabetes Annals of Pediatric Endocrinology & Metabolism Painful neuropathy Autonomic neuropathy Type 1 diabetes mellitus Child Glycemic control |
| title | A case of treatment-induced neuropathy in an adolescent with type 1 diabetes |
| title_full | A case of treatment-induced neuropathy in an adolescent with type 1 diabetes |
| title_fullStr | A case of treatment-induced neuropathy in an adolescent with type 1 diabetes |
| title_full_unstemmed | A case of treatment-induced neuropathy in an adolescent with type 1 diabetes |
| title_short | A case of treatment-induced neuropathy in an adolescent with type 1 diabetes |
| title_sort | case of treatment induced neuropathy in an adolescent with type 1 diabetes |
| topic | Painful neuropathy Autonomic neuropathy Type 1 diabetes mellitus Child Glycemic control |
| url | http://e-apem.org/upload/pdf/apem-2019-24-3-203.pdf |
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