Switching off Bacterial Flagellar Biogenesis by YdiU-Mediated UMPylation of FlhDC

Switching off Bacterial Flagellar Biogenesis by YdiU-Mediated UMPylation of FlhDC

ABSTRACT Bacterial flagellin activates the host immune system and triggers pyroptosis. Salmonella reduces flagellin expression when it survives within host cells. Here, we found that the UMPylator YdiU significantly altered the Salmonella flagellar biogenesis process upon host cell entry. The expres...

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Bibliographic Details
Main Authors: Yue Ma, Yingying Yue, Haihong Jia, Nannan Song, Li Zhai, Weiwei Wang, Cuiling Li, Bingqing Li
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:mBio
Subjects:
FlhDC
Salmonella
UMPylation
YdiU
flagellar gene regulation
Online Access:https://journals.asm.org/doi/10.1128/mbio.00249-22

Internet

https://journals.asm.org/doi/10.1128/mbio.00249-22

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