Identification of NUDT15*3 Variant in the Bangladeshi Population using Allele-Specific PCR

Identification of NUDT15*3 Variant in the Bangladeshi Population using Allele-Specific PCR

Background: Thiopurines are a class of immunosuppressive drugs that are often the mainstay of treatment for diverse immunological and malignant conditions. The protein product of the gene NUDT15 (nudix hydrolase 15) has been linked to thiopurine metabolism as it negatively regulates thiopurine act...

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Bibliographic Details
Main Authors: Drishty Badhon Sarker, Md. Mahmudul Hasan Akash, Abu Ashfaqur Sajib, Sharif Akhteruzzaman
Format: Article
Language:English
Published: Mary Ann Liebert 2022-06-01
Series:Re:GEN Open
Subjects:
variant
population
thiopurines
allele-specific primer
genotype
Online Access:https://www.liebertpub.com/doi/full/10.1089/REGEN.2022.0033

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