Isobolographic Antinociception of Nonsteroidal Anti-inflammatory Drugs in Rodent Formalin Orofacial Pain

Isobolographic Antinociception of Nonsteroidal Anti-inflammatory Drugs in Rodent Formalin Orofacial Pain

Background: Diverse studies suggest that non-steroidal anti-inflammatory drugs (NSAIDs) induce antinociception through the inhibition of cyclooxygenases. Objectives: This study evaluated the effect of NSAIDs in inducing antinociception either alone or in combination in mice formalin orofacial pain....

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Bibliographic Details
Main Authors: Viviana Noriega, Fernando Sierralta, Nicolás Aranda, Ramón Sotomayor-Zárate, Paula Poblete, Juan Carlos Prieto, Hugo F Miranda
Format: Article
Language:English
Published: Mazandaran University of Medical Sciences 2020-09-01
Series:Pharmaceutical and Biomedical Research
Subjects:
nonsteroidal anti-inflammatory drugs
orofacial pain
isobolographic analysis
synergism
Online Access:http://pbr.mazums.ac.ir/article-1-286-en.html

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