Arylpyrrole and fipronil analogues that inhibit the motility and/or development of Haemonchus contortus in vitro

Arylpyrrole and fipronil analogues that inhibit the motility and/or development of Haemonchus contortus in vitro

Due to widespread drug resistance in parasitic nematodes, there is a need to develop new anthelmintics. Given the cost and time involved in developing a new drug, the repurposing of known chemicals can be a promising, alternative approach. In this context, we tested a library (n = 600) of natural pr...

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Bibliographic Details
Main Authors: H.M.P. Dilrukshi Herath, Hongjian Song, Sarah Preston, Abdul Jabbar, Tao Wang, Sean L. McGee, Andreas Hofmann, Jose Garcia-Bustos, Bill C.H. Chang, Anson V. Koehler, Yuxiu Liu, Qiaoqiao Ma, Pengxiang Zhang, Qiqi Zhao, Qingmin Wang, Robin B. Gasser
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:International Journal for Parasitology: Drugs and Drug Resistance
Online Access:http://www.sciencedirect.com/science/article/pii/S2211320718300496

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