Antigen footprint governs activation of the B cell receptor
The antigen-B-cell-receptor interaction is the driving force of terminal B cell development that spans from B cell activation to antibody secreting plasma cells. Here authors determine, using DNA-PAINT super-resolution microscopy, how antigen affinity and valency define antigen binding to BCR in an...
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Bibliographic Details
| Main Authors: |
Alexey Ferapontov,
Marjan Omer,
Isabelle Baudrexel,
Jesper Sejrup Nielsen,
Daniel Miotto Dupont,
Kristian Juul-Madsen,
Philipp Steen,
Alexandra S. Eklund,
Steffen Thiel,
Thomas Vorup-Jensen,
Ralf Jungmann,
Jørgen Kjems,
Søren Egedal Degn |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2023-02-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-023-36672-0
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