The Down Syndrome Biomarker Initiative (DSBI) Pilot: Proof of Concept for Deep Phenotyping of Alzheimer’s Disease Biomarkers in Down Syndrome

The Down Syndrome Biomarker Initiative (DSBI) Pilot: Proof of Concept for Deep Phenotyping of Alzheimer’s Disease Biomarkers in Down Syndrome

To gain further knowledge on the preclinical phase of AD, we sought to characterize cognitive performance, volumetric MRI, amyloid PET, FDG PET, retinal amyloid, and plasma biomarkers in a cohort of non-demented adults with Down Syndrome (DS). The goal of the Down Syndrome Biomarker Initiative (DSB...

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Bibliographic Details
Main Authors: Michael eRafii, Hannah eWishnek, James eBrewer, Michael eDonohue, Seth eNess, William eMobley, Paul eAisen, Robert eRissman
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Amyloid
Down Syndrome
Plasma
Retina
MRI
PET
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00239/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2015.00239/full

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