Potential drug‐drug interaction between tolvaptan and warfarin in a geriatric patient with heart failure

Potential drug‐drug interaction between tolvaptan and warfarin in a geriatric patient with heart failure

Abstract Tolvaptan is a key drug for patients with heart failure. Here, we present a 92‐year‐old woman, whose PT‐INR/dose increased from 1.74 to 3.30 after warfarin and tolvaptan co‐administration, and resulted in a large cerebral infarction after warfarin dose down. Therefore, the interaction betwe...

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Bibliographic Details
Main Authors: Satomi Nimura, Kanayuki Kitahara, Kazuyo Ueshima, Yasuhide Mochizuki, Kenji Momo, Toshiro Shinke, Tadanori Sasaki
Format: Article
Language:English
Published: Wiley 2022-04-01
Series:Clinical Case Reports
Subjects:
cerebral infarction
drug‐drug interaction
heart failure
tolvaptan
warfarin
Online Access:https://doi.org/10.1002/ccr3.5592

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